| Publikationstyp: | Buchbeitrag |
| Art der Begutachtung: | Editorial review |
| Titel: | Bag bioreactor based on wave-induced motion : characteristics and applications |
| Autor/-in: | Eibl-Schindler, Regine Werner, Sören Eibl, Dieter |
| DOI: | 10.1007/10_2008_15 |
| Erschienen in: | Disposable Bioreactors |
| Herausgeber/-in des übergeordneten Werkes: | Eibl-Schindler, Regine Eibl, Dieter |
| Seite(n): | 55 |
| Seiten bis: | 87 |
| Erscheinungsdatum: | 2010 |
| Reihe: | Advances in Biochemical Engineering / Biotechnology |
| Reihenzählung: | 115 |
| Verlag / Hrsg. Institution: | Springer |
| Verlag / Hrsg. Institution: | Berlin |
| ISBN: | 978-3-642-01871-8 978-3-642-01872-5 |
| Sprache: | Englisch |
| Schlagwörter: | Animal cells; Biological insecticides; Biotransformation; Immunomodulator; Plant cells; Seed inoculum; Wave-mixed bag bioreactor |
| Fachgebiet (DDC): | 660: Technische Chemie |
| Zusammenfassung: | Today wave-mixed bag bioreactors are common devices in modern biotechnological processes where simple, safe and flexible production has top priority. Numerous studies that have been published on ex vivo generation of cells, viruses and therapeutic agents during the last 10 years have confirmed their suitability and even superiority to stirred bioreactors made from glass or stainless steel for animal as well as plant cell cultivations. In these studies the wave-mixed bag bioreactors enabled middle to high cell density and adequate productivity in laboratory and pilot scale. This mainly results from low-shear conditions and highly efficient oxygen transfer for cell cultures, as demonstrated for the widely used BioWave®. Starting with an overview of wave-mixed bag bioreactors and their common operation strategies, this chapter delineates engineering aspects of BioWave®, which like Wave Reactor™ and BIOSTAT®CultiBag RM originates from the prototype of a wave-mixed bag bioreactor introduced in 1998. Subsequently, the second part of the chapter focuses on reported BioWave® applications. Conditions and results from cultivations with animal cells, plant cells, microbial cells and nematodes are presented and discussed. |
| URI: | https://digitalcollection.zhaw.ch/handle/11475/2266 |
| Volltext Version: | Publizierte Version |
| Lizenz (gemäss Verlagsvertrag): | Lizenz gemäss Verlagsvertrag |
| Departement: | Life Sciences und Facility Management |
| Organisationseinheit: | Institut für Chemie und Biotechnologie (ICBT) |
| Enthalten in den Sammlungen: | Publikationen Life Sciences und Facility Management |
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Eibl-Schindler, R., Werner, S., & Eibl, D. (2010). Bag bioreactor based on wave-induced motion : characteristics and applications. In R. Eibl-Schindler & D. Eibl (Eds.), Disposable Bioreactors (pp. 55–87). Springer. https://doi.org/10.1007/10_2008_15
Eibl-Schindler, R., Werner, S. and Eibl, D. (2010) ‘Bag bioreactor based on wave-induced motion : characteristics and applications’, in R. Eibl-Schindler and D. Eibl (eds) Disposable Bioreactors. Berlin: Springer, pp. 55–87. Available at: https://doi.org/10.1007/10_2008_15.
R. Eibl-Schindler, S. Werner, and D. Eibl, “Bag bioreactor based on wave-induced motion : characteristics and applications,” in Disposable Bioreactors, R. Eibl-Schindler and D. Eibl, Eds. Berlin: Springer, 2010, pp. 55–87. doi: 10.1007/10_2008_15.
EIBL-SCHINDLER, Regine, Sören WERNER und Dieter EIBL, 2010. Bag bioreactor based on wave-induced motion : characteristics and applications. In: Regine EIBL-SCHINDLER und Dieter EIBL (Hrsg.), Disposable Bioreactors. Berlin: Springer. S. 55–87. ISBN 978-3-642-01871-8
Eibl-Schindler, Regine, Sören Werner, and Dieter Eibl. 2010. “Bag Bioreactor Based on Wave-Induced Motion : Characteristics and Applications.” In Disposable Bioreactors, edited by Regine Eibl-Schindler and Dieter Eibl, 55–87. Berlin: Springer. https://doi.org/10.1007/10_2008_15.
Eibl-Schindler, Regine, et al. “Bag Bioreactor Based on Wave-Induced Motion : Characteristics and Applications.” Disposable Bioreactors, edited by Regine Eibl-Schindler and Dieter Eibl, Springer, 2010, pp. 55–87, https://doi.org/10.1007/10_2008_15.
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