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dc.contributor.authorEibl-Schindler, Regine-
dc.contributor.authorWerner, Sören-
dc.contributor.authorEibl, Dieter-
dc.date.accessioned2018-01-30T12:48:46Z-
dc.date.available2018-01-30T12:48:46Z-
dc.date.issued2010-
dc.identifier.isbn978-3-642-01871-8de_CH
dc.identifier.isbn978-3-642-01872-5de_CH
dc.identifier.urihttps://digitalcollection.zhaw.ch/handle/11475/2266-
dc.description.abstractToday wave-mixed bag bioreactors are common devices in modern biotechnological processes where simple, safe and flexible production has top priority. Numerous studies that have been published on ex vivo generation of cells, viruses and therapeutic agents during the last 10 years have confirmed their suitability and even superiority to stirred bioreactors made from glass or stainless steel for animal as well as plant cell cultivations. In these studies the wave-mixed bag bioreactors enabled middle to high cell density and adequate productivity in laboratory and pilot scale. This mainly results from low-shear conditions and highly efficient oxygen transfer for cell cultures, as demonstrated for the widely used BioWave®. Starting with an overview of wave-mixed bag bioreactors and their common operation strategies, this chapter delineates engineering aspects of BioWave®, which like Wave Reactor™ and BIOSTAT®CultiBag RM originates from the prototype of a wave-mixed bag bioreactor introduced in 1998. Subsequently, the second part of the chapter focuses on reported BioWave® applications. Conditions and results from cultivations with animal cells, plant cells, microbial cells and nematodes are presented and discussed. de_CH
dc.language.isoende_CH
dc.publisherSpringerde_CH
dc.relation.ispartofDisposable Bioreactorsde_CH
dc.relation.ispartofseriesAdvances in Biochemical Engineering / Biotechnologyde_CH
dc.rightsLicence according to publishing contractde_CH
dc.subjectAnimal cellsde_CH
dc.subjectBiological insecticidesde_CH
dc.subjectBiotransformationde_CH
dc.subjectImmunomodulatorde_CH
dc.subjectPlant cellsde_CH
dc.subjectSeed inoculumde_CH
dc.subjectWave-mixed bag bioreactorde_CH
dc.subject.ddc660: Technische Chemiede_CH
dc.titleBag bioreactor based on wave-induced motion : characteristics and applicationsde_CH
dc.typeBuchbeitragde_CH
dcterms.typeTextde_CH
zhaw.departementLife Sciences und Facility Managementde_CH
zhaw.organisationalunitInstitut für Chemie und Biotechnologie (ICBT)de_CH
zhaw.publisher.placeBerlinde_CH
dc.identifier.doi10.1007/10_2008_15de_CH
zhaw.funding.euNode_CH
zhaw.originated.zhawYesde_CH
zhaw.pages.end87de_CH
zhaw.pages.start55de_CH
zhaw.parentwork.editorEibl-Schindler, Regine-
zhaw.parentwork.editorEibl, Dieter-
zhaw.publication.statuspublishedVersionde_CH
zhaw.series.number115de_CH
zhaw.publication.reviewEditorial reviewde_CH
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Eibl-Schindler, R., Werner, S., & Eibl, D. (2010). Bag bioreactor based on wave-induced motion : characteristics and applications. In R. Eibl-Schindler & D. Eibl (Eds.), Disposable Bioreactors (pp. 55–87). Springer. https://doi.org/10.1007/10_2008_15
Eibl-Schindler, R., Werner, S. and Eibl, D. (2010) ‘Bag bioreactor based on wave-induced motion : characteristics and applications’, in R. Eibl-Schindler and D. Eibl (eds) Disposable Bioreactors. Berlin: Springer, pp. 55–87. Available at: https://doi.org/10.1007/10_2008_15.
R. Eibl-Schindler, S. Werner, and D. Eibl, “Bag bioreactor based on wave-induced motion : characteristics and applications,” in Disposable Bioreactors, R. Eibl-Schindler and D. Eibl, Eds. Berlin: Springer, 2010, pp. 55–87. doi: 10.1007/10_2008_15.
EIBL-SCHINDLER, Regine, Sören WERNER und Dieter EIBL, 2010. Bag bioreactor based on wave-induced motion : characteristics and applications. In: Regine EIBL-SCHINDLER und Dieter EIBL (Hrsg.), Disposable Bioreactors. Berlin: Springer. S. 55–87. ISBN 978-3-642-01871-8
Eibl-Schindler, Regine, Sören Werner, and Dieter Eibl. 2010. “Bag Bioreactor Based on Wave-Induced Motion : Characteristics and Applications.” In Disposable Bioreactors, edited by Regine Eibl-Schindler and Dieter Eibl, 55–87. Berlin: Springer. https://doi.org/10.1007/10_2008_15.
Eibl-Schindler, Regine, et al. “Bag Bioreactor Based on Wave-Induced Motion : Characteristics and Applications.” Disposable Bioreactors, edited by Regine Eibl-Schindler and Dieter Eibl, Springer, 2010, pp. 55–87, https://doi.org/10.1007/10_2008_15.


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