In vivo confirmation of hydration-induced changes in human-skin thickness, roughness and interaction with the environment

Dabrowska, Agnieszka K.; Adlhart, Christian; Spano, Fabrizio; Rotaru, Gelu-Marius; Derler, Siegfried; Zhai, Lina; Spencer, Nicolas D.; Rossi, René M.

doi:10.1116/1.4962547

Please use this identifier to cite or link to this item: https://doi.org/10.21256/zhaw-1573

Publication type:	Article in scientific journal
Type of review:	Peer review (publication)
Title:	In vivo confirmation of hydration-induced changes in human-skin thickness, roughness and interaction with the environment
Authors:	Dabrowska, Agnieszka K. Adlhart, Christian Spano, Fabrizio Rotaru, Gelu-Marius Derler, Siegfried Zhai, Lina Spencer, Nicolas D. Rossi, René M.
DOI:	10.1116/1.4962547 10.21256/zhaw-1573
Published in:	Biointerphases
Volume(Issue):	11
Issue:	3
Issue Date:	Aug-2016
Publisher / Ed. Institution:	American Institute of Physics
Publisher / Ed. Institution:	Maryland
ISSN:	1934-8630 1559-4106
Language:	English
Subjects:	Skin; Raman spectra; Spectral properties; Three dimensional microscopy; Proteins
Subject (DDC):	610: Medicine and health
Abstract:	Skin properties, structure and performance can be influenced by many internal and external factors, such as age, gender, lifestyle, skin diseases and a hydration level that can vary in relation to the environment. The aim of this work was to demonstrate the multifaceted influence of water on human skin through a combination of in vivo confocal Raman spectroscopy and images of volar-forearm skin captured with laser scanning confocal microscopy. By means of this pilot study, we have both qualitatively and quantitatively studied the influence of changing the depth-dependent hydration level of the stratum corneum (SC) on the real contact area (RCA), surface roughness and the dimensions of the primary lines and presented a new method for characterising the contact area for different states of the skin. The hydration level of the skin and the thickness of the SC increased significantly due to uptake of moisture derived from liquid water or, to a much lesser extent, from humidity present in the environment. Hydrated skin was smoother and exhibited higher RCA values. The highest rates of water uptake were observed for the upper few μm of skin and for short exposure times.
URI:	https://digitalcollection.zhaw.ch/handle/11475/2185
Fulltext version:	Published version
License (according to publishing contract):	CC BY 4.0: Attribution 4.0 International
Departement:	Life Sciences and Facility Management
Organisational Unit:	Institute of Chemistry and Biotechnology (ICBT)
Appears in collections:	Publikationen Life Sciences und Facility Management

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Dabrowska, A. K., Adlhart, C., Spano, F., Rotaru, G.-M., Derler, S., Zhai, L., Spencer, N. D., & Rossi, R. M. (2016). In vivo confirmation of hydration-induced changes in human-skin thickness, roughness and interaction with the environment. Biointerphases, 11(3). https://doi.org/10.1116/1.4962547

Dabrowska, A.K. et al. (2016) ‘In vivo confirmation of hydration-induced changes in human-skin thickness, roughness and interaction with the environment’, Biointerphases, 11(3). Available at: https://doi.org/10.1116/1.4962547.

A. K. Dabrowska et al., “In vivo confirmation of hydration-induced changes in human-skin thickness, roughness and interaction with the environment,” Biointerphases, vol. 11, no. 3, Aug. 2016, doi: 10.1116/1.4962547.

DABROWSKA, Agnieszka K., Christian ADLHART, Fabrizio SPANO, Gelu-Marius ROTARU, Siegfried DERLER, Lina ZHAI, Nicolas D. SPENCER und René M. ROSSI, 2016. In vivo confirmation of hydration-induced changes in human-skin thickness, roughness and interaction with the environment. Biointerphases. August 2016. Bd. 11, Nr. 3. DOI 10.1116/1.4962547

Dabrowska, Agnieszka K., Christian Adlhart, Fabrizio Spano, Gelu-Marius Rotaru, Siegfried Derler, Lina Zhai, Nicolas D. Spencer, and René M. Rossi. 2016. “In Vivo Confirmation of Hydration-Induced Changes in Human-Skin Thickness, Roughness and Interaction with the Environment.” Biointerphases 11 (3). https://doi.org/10.1116/1.4962547.

Dabrowska, Agnieszka K., et al. “In Vivo Confirmation of Hydration-Induced Changes in Human-Skin Thickness, Roughness and Interaction with the Environment.” Biointerphases, vol. 11, no. 3, Aug. 2016, https://doi.org/10.1116/1.4962547.