Please use this identifier to cite or link to this item: https://doi.org/10.21256/zhaw-1573
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dc.contributor.authorDabrowska, Agnieszka K.-
dc.contributor.authorAdlhart, Christian-
dc.contributor.authorSpano, Fabriziano-
dc.contributor.authorRotaru, Gelu-Marius-
dc.contributor.authorDerler, Siegfried-
dc.contributor.authorZhai, Lina-
dc.contributor.authorSpencer, Nicolas D.-
dc.contributor.authorRossi, René M.-
dc.date.accessioned2018-01-25T10:31:50Z-
dc.date.available2018-01-25T10:31:50Z-
dc.date.issued2016-08-
dc.identifier.issn1934-8630de_CH
dc.identifier.urihttps://digitalcollection.zhaw.ch/handle/11475/2185-
dc.description.abstractSkin properties, structure and performance can be influenced by many internal and external factors, such as age, gender, lifestyle, skin diseases and a hydration level that can vary in relation to the environment. The aim of this work was to demonstrate the multifaceted influence of water on human skin through a combination of in vivo confocal Raman spectroscopy and images of volar-forearm skin captured with laser scanning confocal microscopy. By means of this pilot study, we have both qualitatively and quantitatively studied the influence of changing the depth-dependent hydration level of the stratum corneum (SC) on the real contact area (RCA), surface roughness and the dimensions of the primary lines and presented a new method for characterising the contact area for different states of the skin. The hydration level of the skin and the thickness of the SC increased significantly due to uptake of moisture derived from liquid water or, to a much lesser extent, from humidity present in the environment. Hydrated skin was smoother and exhibited higher RCA values. The highest rates of water uptake were observed for the upper few μm of skin and for short exposure times.de_CH
dc.language.isoende_CH
dc.publisherA I P Publishing LLCde_CH
dc.relation.ispartofBiointerphasesde_CH
dc.rightshttp://creativecommons.org/licenses/by/4.0/de_CH
dc.subjectSkinde_CH
dc.subjectRaman spectrade_CH
dc.subjectSpectral propertiesde_CH
dc.subjectThree dimensional microscopyde_CH
dc.subjectProteinsde_CH
dc.subject.ddc610: Medizin, Gesundheitde_CH
dc.titleIn vivo confirmation of hydration-induced changes in human-skin thickness, roughness and interaction with the environmentde_CH
dc.typeBeitrag in wissenschaftlicher Zeitschriftde_CH
dc.typeTextde_CH
zhaw.departementLife Sciences und Facility Managementde_CH
zhaw.organisationalunitInstitut für Chemie und Biotechnologie (ICBT)de_CH
zhaw.publisher.placeMarylandde_CH
dc.identifier.doi10.1116/1.4962547de_CH
dc.identifier.doi10.21256/zhaw-1573de_CH
zhaw.funding.euNode_CH
zhaw.issue3de_CH
zhaw.originated.zhawYesde_CH
zhaw.publication.statuspublishedVersionde_CH
zhaw.volume11de_CH
zhaw.publication.reviewPeer review (Publikation)de_CH
zhaw.monitoring.oajournalNot specifiedde_CH
Appears in Collections:Publikationen Life Sciences und Facility Management

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