Please use this identifier to cite or link to this item:
https://doi.org/10.21256/zhaw-2770
Publication type: | Conference paper |
Type of review: | Not specified |
Title: | Gene expression signatures of pathways alterations in tumor cells caused by plant extracts |
Authors: | Wagschal, Isabelle Eggenschwiler, Jenny von Balthazar, Leopold Patrignani, Andrea Rehrauer, Hubert Schlapbach, Ralph Ramos, Mac H. Viviani, Angelika |
DOI: | 10.21256/zhaw-2770 |
Published in: | Medicina |
Volume(Issue): | 67 |
Issue: | Suppl. II |
Page(s): | 97 |
Pages to: | 106 |
Conference details: | International Symposium: New Directions in Cancer Management, Academia Nacional de Medicina, Buenos Aires, Argentina, 6-8 June 2007 |
Issue Date: | 2007 |
Publisher / Ed. Institution: | Fundación Revista Medicina |
ISSN: | 0025-7680 1669-9106 |
Language: | English |
Subject (DDC): | 616: Internal medicine and diseases |
Abstract: | Extracts of Viscum album from different host trees (Iscador®Qu, M, P and A) and isolated mistletoe lectin showed distinct gene-expression profiles using cDNA microarrays. We were able to confirm that genes of apoptosis, the cell cycle and the immune system were affected by mistletoe preparations and we also found that signal transduction, cell communication and cancer related pathways were overregulated in the tested breast cancer (HCC-1937, MCF-7, KPL-1, Mfm-223) and lymphoma cell lines (WSZ-NHL). The effect of a specific mistletoe extract on a particular cell line was individual, so that the distinction between the reaction of the cell type and/or the influence of the mistletoe preparation could be used in targeted mistletoe therapy. |
URI: | https://digitalcollection.zhaw.ch/handle/11475/15010 |
Fulltext version: | Published version |
License (according to publishing contract): | CC BY 4.0: Attribution 4.0 International |
Departement: | Life Sciences and Facility Management |
Organisational Unit: | Institute of Chemistry and Biotechnology (ICBT) |
Appears in collections: | Publikationen Life Sciences und Facility Management |
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Wagschal, I., Eggenschwiler, J., von Balthazar, L., Patrignani, A., Rehrauer, H., Schlapbach, R., Ramos, M. H., & Viviani, A. (2007). Gene expression signatures of pathways alterations in tumor cells caused by plant extracts [Conference paper]. Medicina, 67(Suppl. II), 97–106. https://doi.org/10.21256/zhaw-2770
Wagschal, I. et al. (2007) ‘Gene expression signatures of pathways alterations in tumor cells caused by plant extracts’, in Medicina. Fundación Revista Medicina, pp. 97–106. Available at: https://doi.org/10.21256/zhaw-2770.
I. Wagschal et al., “Gene expression signatures of pathways alterations in tumor cells caused by plant extracts,” in Medicina, 2007, vol. 67, no. Suppl. II, pp. 97–106. doi: 10.21256/zhaw-2770.
WAGSCHAL, Isabelle, Jenny EGGENSCHWILER, Leopold VON BALTHAZAR, Andrea PATRIGNANI, Hubert REHRAUER, Ralph SCHLAPBACH, Mac H. RAMOS und Angelika VIVIANI, 2007. Gene expression signatures of pathways alterations in tumor cells caused by plant extracts. In: Medicina. Conference paper. Fundación Revista Medicina. 2007. S. 97–106
Wagschal, Isabelle, Jenny Eggenschwiler, Leopold von Balthazar, Andrea Patrignani, Hubert Rehrauer, Ralph Schlapbach, Mac H. Ramos, and Angelika Viviani. 2007. “Gene Expression Signatures of Pathways Alterations in Tumor Cells Caused by Plant Extracts.” Conference paper. In Medicina, 67:97–106. Fundación Revista Medicina. https://doi.org/10.21256/zhaw-2770.
Wagschal, Isabelle, et al. “Gene Expression Signatures of Pathways Alterations in Tumor Cells Caused by Plant Extracts.” Medicina, vol. 67, no. Suppl. II, Fundación Revista Medicina, 2007, pp. 97–106, https://doi.org/10.21256/zhaw-2770.
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