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Publikationstyp: Konferenz: Paper
Art der Begutachtung: Keine Angabe
Titel: Gene expression signatures of pathways alterations in tumor cells caused by plant extracts
Autor/-in: Wagschal, Isabelle
Eggenschwiler, Jenny
von Balthazar, Leopold
Patrignani, Andrea
Rehrauer, Hubert
Schlapbach, Ralph
Ramos, Mac H.
Viviani, Angelika
DOI: 10.21256/zhaw-2770
Erschienen in: Medicina
Band(Heft): 67
Heft: Suppl. II
Seite(n): 97
Seiten bis: 106
Angaben zur Konferenz: International Symposium: New Directions in Cancer Management, Academia Nacional de Medicina, Buenos Aires, Argentina, 6-8 June 2007
Erscheinungsdatum: 2007
Verlag / Hrsg. Institution: Fundación Revista Medicina
ISSN: 0025-7680
1669-9106
Sprache: Englisch
Fachgebiet (DDC): 616: Innere Medizin und Krankheiten
Zusammenfassung: Extracts of Viscum album from different host trees (Iscador®Qu, M, P and A) and isolated mistletoe lectin showed distinct gene-expression profiles using cDNA microarrays. We were able to confirm that genes of apoptosis, the cell cycle and the immune system were affected by mistletoe preparations and we also found that signal transduction, cell communication and cancer related pathways were overregulated in the tested breast cancer (HCC-1937, MCF-7, KPL-1, Mfm-223) and lymphoma cell lines (WSZ-NHL). The effect of a specific mistletoe extract on a particular cell line was individual, so that the distinction between the reaction of the cell type and/or the influence of the mistletoe preparation could be used in targeted mistletoe therapy.
URI: https://digitalcollection.zhaw.ch/handle/11475/15010
Volltext Version: Publizierte Version
Lizenz (gemäss Verlagsvertrag): CC BY 4.0: Namensnennung 4.0 International
Departement: Life Sciences und Facility Management
Organisationseinheit: Institut für Chemie und Biotechnologie (ICBT)
Enthalten in den Sammlungen:Publikationen Life Sciences und Facility Management

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Wagschal, I., Eggenschwiler, J., von Balthazar, L., Patrignani, A., Rehrauer, H., Schlapbach, R., Ramos, M. H., & Viviani, A. (2007). Gene expression signatures of pathways alterations in tumor cells caused by plant extracts [Conference paper]. Medicina, 67(Suppl. II), 97–106. https://doi.org/10.21256/zhaw-2770
Wagschal, I. et al. (2007) ‘Gene expression signatures of pathways alterations in tumor cells caused by plant extracts’, in Medicina. Fundación Revista Medicina, pp. 97–106. Available at: https://doi.org/10.21256/zhaw-2770.
I. Wagschal et al., “Gene expression signatures of pathways alterations in tumor cells caused by plant extracts,” in Medicina, 2007, vol. 67, no. Suppl. II, pp. 97–106. doi: 10.21256/zhaw-2770.
WAGSCHAL, Isabelle, Jenny EGGENSCHWILER, Leopold VON BALTHAZAR, Andrea PATRIGNANI, Hubert REHRAUER, Ralph SCHLAPBACH, Mac H. RAMOS und Angelika VIVIANI, 2007. Gene expression signatures of pathways alterations in tumor cells caused by plant extracts. In: Medicina. Conference paper. Fundación Revista Medicina. 2007. S. 97–106
Wagschal, Isabelle, Jenny Eggenschwiler, Leopold von Balthazar, Andrea Patrignani, Hubert Rehrauer, Ralph Schlapbach, Mac H. Ramos, and Angelika Viviani. 2007. “Gene Expression Signatures of Pathways Alterations in Tumor Cells Caused by Plant Extracts.” Conference paper. In Medicina, 67:97–106. Fundación Revista Medicina. https://doi.org/10.21256/zhaw-2770.
Wagschal, Isabelle, et al. “Gene Expression Signatures of Pathways Alterations in Tumor Cells Caused by Plant Extracts.” Medicina, vol. 67, no. Suppl. II, Fundación Revista Medicina, 2007, pp. 97–106, https://doi.org/10.21256/zhaw-2770.


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