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Publikationstyp: Beitrag in wissenschaftlicher Zeitschrift
Art der Begutachtung: Peer review (Publikation)
Titel: Thermography : high sensitivity and specificity diagnosing contact dermatitis in patch testing
Autor/-in: Anzengruber, Florian
Alotaibi, Fayez
Kaufmann, Lilian S.
Ghosh, Adhideb
Oswald, Martin R.
Maul, Julia-Tatjana
Meier Käppeli, Barbara Katharina
French, Lars E.
Bonmarin, Mathias
Navarini, Alexander A.
DOI: 10.21256/zhaw-3414
10.1016/j.alit.2018.12.001
Erschienen in: Allergology International
Band(Heft): 68
Heft: 2
Erscheinungsdatum: 2018
Verlag / Hrsg. Institution: Japanese Society of Allergology
ISSN: 1323-8930
1440-1592
Sprache: Englisch
Schlagwörter: Allergic contact dermatitis; Contact allergy; Infrared; Irritant contact dermatitis; Patch testing
Fachgebiet (DDC): 616: Innere Medizin und Krankheiten
Zusammenfassung: Background: Patch testing of contact allergens to diagnose allergic contact dermatitis (ACD) is a traditional, useful tool. The most important decision is the distinction between allergic and irritant reactions, as this has direct implications on diagnosis and management. Our objective was to evaluate a new method of non-contact infrared reading of patch tests. Secondary objectives included a possible correlation between the intensity of the patch test reaction and temperature change. Methods: 420 positive reactions from patients were included in our study. An independent patch test reader assessed the positive reactions and classified them as allergic (of intensity + to +++) or irritant (IR). At the same time, a forward-looking infrared (FLIR) camera attachment for an iPhone was used to acquire infrared thermal images of the patch tests, and images were analyzed using the FLIR ONE app. Results: Allergic patch test reactions were characterized by temperature increases of 0.72 ± 0.67°C compared to surrounding skin. Irritant reactions only resulted in 0.17 ± 0.31 °C temperature increase. The mean temperature difference between the two groups was highly significant (p < 0.0001) and therefore was used to predict the type of contact dermatitis. Conclusions: Thermography is a reliable and effective way to distinguish between allergic and irritant contact dermatitis.
Weitere Angaben: In Press
URI: https://digitalcollection.zhaw.ch/handle/11475/14450
Volltext Version: Publizierte Version
Lizenz (gemäss Verlagsvertrag): CC BY-NC-ND 4.0: Namensnennung - Nicht kommerziell - Keine Bearbeitungen 4.0 International
Departement: School of Engineering
Organisationseinheit: Institute of Computational Physics (ICP)
Enthalten in den Sammlungen:Publikationen School of Engineering

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