Thermography : high sensitivity and specificity diagnosing contact dermatitis in patch testing

Anzengruber, Florian; Alotaibi, Fayez; Kaufmann, Lilian S.; Ghosh, Adhideb; Oswald, Martin R.; Maul, Julia-Tatjana; Meier Käppeli, Barbara Katharina; French, Lars E.; Bonmarin, Mathias; Navarini, Alexander A.

doi:10.21256/zhaw-3414

Please use this identifier to cite or link to this item: https://doi.org/10.21256/zhaw-3414

Publication type:	Article in scientific journal
Type of review:	Peer review (publication)
Title:	Thermography : high sensitivity and specificity diagnosing contact dermatitis in patch testing
Authors:	Anzengruber, Florian Alotaibi, Fayez Kaufmann, Lilian S. Ghosh, Adhideb Oswald, Martin R. Maul, Julia-Tatjana Meier Käppeli, Barbara Katharina French, Lars E. Bonmarin, Mathias Navarini, Alexander A.
DOI:	10.21256/zhaw-3414 10.1016/j.alit.2018.12.001
Published in:	Allergology International
Volume(Issue):	68
Issue:	2
Issue Date:	2018
Publisher / Ed. Institution:	Japanese Society of Allergology
ISSN:	1323-8930 1440-1592
Language:	English
Subjects:	Allergic contact dermatitis; Contact allergy; Infrared; Irritant contact dermatitis; Patch testing
Subject (DDC):	616: Internal medicine and diseases
Abstract:	Background: Patch testing of contact allergens to diagnose allergic contact dermatitis (ACD) is a traditional, useful tool. The most important decision is the distinction between allergic and irritant reactions, as this has direct implications on diagnosis and management. Our objective was to evaluate a new method of non-contact infrared reading of patch tests. Secondary objectives included a possible correlation between the intensity of the patch test reaction and temperature change. Methods: 420 positive reactions from patients were included in our study. An independent patch test reader assessed the positive reactions and classified them as allergic (of intensity + to +++) or irritant (IR). At the same time, a forward-looking infrared (FLIR) camera attachment for an iPhone was used to acquire infrared thermal images of the patch tests, and images were analyzed using the FLIR ONE app. Results: Allergic patch test reactions were characterized by temperature increases of 0.72 ± 0.67°C compared to surrounding skin. Irritant reactions only resulted in 0.17 ± 0.31 °C temperature increase. The mean temperature difference between the two groups was highly significant (p < 0.0001) and therefore was used to predict the type of contact dermatitis. Conclusions: Thermography is a reliable and effective way to distinguish between allergic and irritant contact dermatitis.
Further description:	In Press
URI:	https://digitalcollection.zhaw.ch/handle/11475/14450
Fulltext version:	Published version
License (according to publishing contract):	CC BY-NC-ND 4.0: Attribution - Non commercial - No derivatives 4.0 International
Departement:	School of Engineering
Organisational Unit:	Institute of Computational Physics (ICP)
Appears in collections:	Publikationen School of Engineering

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Anzengruber, F., Alotaibi, F., Kaufmann, L. S., Ghosh, A., Oswald, M. R., Maul, J.-T., Meier Käppeli, B. K., French, L. E., Bonmarin, M., & Navarini, A. A. (2018). Thermography : high sensitivity and specificity diagnosing contact dermatitis in patch testing. Allergology International, 68(2). https://doi.org/10.21256/zhaw-3414

Anzengruber, F. et al. (2018) ‘Thermography : high sensitivity and specificity diagnosing contact dermatitis in patch testing’, Allergology International, 68(2). Available at: https://doi.org/10.21256/zhaw-3414.

F. Anzengruber et al., “Thermography : high sensitivity and specificity diagnosing contact dermatitis in patch testing,” Allergology International, vol. 68, no. 2, 2018, doi: 10.21256/zhaw-3414.

ANZENGRUBER, Florian, Fayez ALOTAIBI, Lilian S. KAUFMANN, Adhideb GHOSH, Martin R. OSWALD, Julia-Tatjana MAUL, Barbara Katharina MEIER KÄPPELI, Lars E. FRENCH, Mathias BONMARIN und Alexander A. NAVARINI, 2018. Thermography : high sensitivity and specificity diagnosing contact dermatitis in patch testing. Allergology International. 2018. Bd. 68, Nr. 2. DOI 10.21256/zhaw-3414

Anzengruber, Florian, Fayez Alotaibi, Lilian S. Kaufmann, Adhideb Ghosh, Martin R. Oswald, Julia-Tatjana Maul, Barbara Katharina Meier Käppeli, Lars E. French, Mathias Bonmarin, and Alexander A. Navarini. 2018. “Thermography : High Sensitivity and Specificity Diagnosing Contact Dermatitis in Patch Testing.” Allergology International 68 (2). https://doi.org/10.21256/zhaw-3414.

Anzengruber, Florian, et al. “Thermography : High Sensitivity and Specificity Diagnosing Contact Dermatitis in Patch Testing.” Allergology International, vol. 68, no. 2, 2018, https://doi.org/10.21256/zhaw-3414.