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dc.contributor.authorAnzengruber, Florian-
dc.contributor.authorAlotaibi, Fayez-
dc.contributor.authorKaufmann, Lilian S.-
dc.contributor.authorGhosh, Adhideb-
dc.contributor.authorOswald, Martin R.-
dc.contributor.authorMaul, Julia-Tatjana-
dc.contributor.authorMeier Käppeli, Barbara Katharina-
dc.contributor.authorFrench, Lars E.-
dc.contributor.authorBonmarin, Mathias-
dc.contributor.authorNavarini, Alexander A.-
dc.descriptionIn Pressde_CH
dc.description.abstractBackground: Patch testing of contact allergens to diagnose allergic contact dermatitis (ACD) is a traditional, useful tool. The most important decision is the distinction between allergic and irritant reactions, as this has direct implications on diagnosis and management. Our objective was to evaluate a new method of non-contact infrared reading of patch tests. Secondary objectives included a possible correlation between the intensity of the patch test reaction and temperature change. Methods: 420 positive reactions from patients were included in our study. An independent patch test reader assessed the positive reactions and classified them as allergic (of intensity + to +++) or irritant (IR). At the same time, a forward-looking infrared (FLIR) camera attachment for an iPhone was used to acquire infrared thermal images of the patch tests, and images were analyzed using the FLIR ONE app. Results: Allergic patch test reactions were characterized by temperature increases of 0.72 ± 0.67°C compared to surrounding skin. Irritant reactions only resulted in 0.17 ± 0.31 °C temperature increase. The mean temperature difference between the two groups was highly significant (p < 0.0001) and therefore was used to predict the type of contact dermatitis. Conclusions: Thermography is a reliable and effective way to distinguish between allergic and irritant contact dermatitis.de_CH
dc.publisherJapanese Society of Allergologyde_CH
dc.relation.ispartofAllergology Internationalde_CH
dc.subjectAllergic contact dermatitisde_CH
dc.subjectContact allergyde_CH
dc.subjectIrritant contact dermatitisde_CH
dc.subjectPatch testingde_CH
dc.subject.ddc616: Innere Medizin und Krankheitende_CH
dc.titleThermography : high sensitivity and specificity diagnosing contact dermatitis in patch testingde_CH
dc.typeBeitrag in wissenschaftlicher Zeitschriftde_CH
zhaw.departementSchool of Engineeringde_CH
zhaw.organisationalunitInstitute of Computational Physics (ICP)de_CH
zhaw.publication.reviewPeer review (Publikation)de_CH
Appears in Collections:Publikationen School of Engineering

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