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Showing results 15 to 34 of 46 < previous   next >
Issue DateTitleInvolved Person(s)
2015How can Computational Fluid Dynamics be used in order to rapidly expand bone marrow derived hMSCs in clinically relevant numbersJossen, Valentin; Eibl, Dieter; Eibl-Schindler, Regine
Apr-2016How to successfully scale up a microcarrier based expansion process of human mesenchymal stem cells from adipose tissueJossen, Valentin; Schirmer, Cedric; Eibl-Schindler, Regine; Kraume, Matthias; Pörtner, Ralf, et al
Jan-2017How to use Computational Fluid Dynamics in the development of cell therapeuticsJossen, Valentin; Eibl-Schindler, Regine; Eibl, Dieter
2021Human adipose stem cells (hASCs) grown on biodegradable microcarriers in serum- and xeno-free medium preserve their undifferentiated statusMuoio, Francesco; Panella, Stefano; Jossen, Valentin; Lindner, Matias; Harder, Yves, et al
Sep-2016Impact of shear stress on cell growth and microcarrier-cell-agglomerate formation in microcarrier-based cultivations of adipose tissue-derived stromal/stem cellsJossen, Valentin; Eibl-Schindler, Regine; Kraume, Matthias; Pörtner, Ralf; Eibl, Dieter
Jun-2013Investigations of fluif flow and microcarrier suspension for hMSC expansion in single-use stirred bioreactorsJossen, Valentin; Kaiser, Stephan; Schirmaier, Carmen; van den Bos, Christian; Eibl, Dieter, et al
2018Manufacturing human mesenchymal stem cells at clinical scale : process and regulatory challengesJossen, Valentin; van den Bos, Christian; Eibl-Schindler, Regine; Eibl, Dieter
2015Mass production of hMSCs : an approach based on stirred single-use bioreactorsEibl-Schindler, Regine; Jossen, Valentin; Eibl, Dieter
26-Nov-2014Mass production of mesenchymal stem cells — impact of bioreactor design and flow conditions on proliferation and differentiationJossen, Valentin; Pörtner, Ralf; Kaiser, Stephan C.; Kraume, Matthias; Eibl, Dieter, et al
Jun-2014Microcarrier-based expansion of adipose tissue and bone marrow derived human mesenchymal stem cells in therapeutically relevant dosesJossen, Valentin; Ott, Anita; Kaiser, Stephan; Brill, Silke; Spicker, Sonja, et al
2014Modification and qualification of a stirred single-use bioreactor for the improved expansion of human mesenchymal stem cells at benchtop scaleJossen, Valentin; Kaiser, Stephan C.; Schirmaier, Carmen; Hermann, Jacqueline; Tappe, Alexander, et al
Mar-2018Multiphase CFD simulations for supporting MC-based hMSC process developmentJossen, Valentin; Eibl-Schindler, Regine; Eibl, Dieter
May-2016Novel probes for pH and dissolved oxygen measurements in cultivations from millilitre to benchtop scaleDemuth, Caspar; Varonier, Joel; Jossen, Valentin; Eibl-Schindler, Regine; Eibl, Dieter
23-Oct-2020Numerical methods for the design and description of in vitro expansion processes of human mesenchymal stem cellsJossen, Valentin; Eibl, Dieter; Eibl, Regine
2014Numerische Strömungsuntersuchungen für die Massstabsübertragung der Expansion von humanen mesenchymalen Stammzellen in gerührten Single-Use BioreaktorenJossen, Valentin; Kaiser, Stephan; Eibl-Schindler, Regine; Eibl, Dieter
19-Sep-2016Nutzung von Sensor Spots zur Bestimmung der Gelöstsauerstoffkonzentration in Single-use Systemen im LabormassstabMaschke, Rüdiger; Werner, Sören; Stalder, Mischa; Jossen, Valentin; Eibl, Dieter
Jun-2015On-line-pH- und -DO-Messungen in Mikrocarrier-basierter hMSC KulturJossen, Valentin; Schirmaier, Carmen; John, Gernot T.; Eibl, Dieter; Eibl-Schindler, Regine
Sep-2014Online pH and DO measurement in microcarrier-based hMSC cultivations performed in single-use spinner flaskJossen, Valentin; Schirmaier, Carmen; John, Gernot; Siehoff, Ann; Eibl, Dieter, et al
2014Optimization of a benchtop single-use bioreactor for the expansion of adipose-tissue and bone marrow derived human mesenchymal stem cellsJossen, Valentin; Kaiser, Stephan; Ott, Anita; Siehoff, Ann; Brill, Silke, et al
May-2016Overview : single-use technologies in biopharmaceutical manufacturingJossen, Valentin