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Publication type: Article in scientific journal
Type of review: Peer review (publication)
Title: The DSM IV diagnoses of melancholic and atypical depression in pregnancy
Authors: Kammerer, Martin
Glover, Vivette
Pinard Anderman, Claudia
Künzli, Hansjörg
Taylor, Alyx
Castelberg, Brida von
Marks, Maureen
DOI: 10.21256/zhaw-4325
Published in: Archives of Women's Mental Health
Volume(Issue): 14
Issue: 1
Pages: 43
Pages to: 48
Issue Date: Feb-2011
Publisher / Ed. Institution: Springer
Publisher / Ed. Institution: Wien
ISSN: 1434-1816
Language: English
Subjects: Diagnosis; Classification; Pregnancy; Melancholic depression; Atypical depression; Depression; Affective disorders; Differential Diagnosis; Diagnostic and Statistical Manual; Symptoms; Structured Clinical Interview; Mothers
Subject (DDC): 616.8: Neurology, diseases of nervous system
Abstract: Atypical and melancholic subtypes of depression based on the Diagnostic and Statistical Manual (DSM) IV are important concepts, especially for biological psychiatry. The aim of this study was to determine whether the symptoms used for the diagnoses of atypical and melancholic depression can distinguish these subtypes during pregnancy. A modified version of the Structured Clinical Interview for DSM IV (SCID interview) was used that allowed assessment of all DSM IV symptoms of melancholic and atypical depression with depressed and non-depressed women in pregnancy. A Swiss cohort of 449 women was interviewed. Four diagnostic groups were compared: women with melancholic, atypical or non specified depression, and those without depression. Seventeen per cent of the cohort met SCID criteria for a depressive episode of depression at least once in pregnancy, with melancholic depression 2.4%, atypical depression 4.4% and non specified depression 10.2%. Many of the symptoms used to distinguish atypical and melancholic depression did not discriminate between these groups during pregnancy. However some, such as mood reactivity, distinct quality of mood and sleep pattern, did discriminate. Differential diagnosis between melancholic and atypical depression in pregnancy needs to be based on pregnancy specific definitions. The possible therapeutic consequences and the neurobiological basis for these findings warrant further research.
Further description: Erworben im Rahmen der Schweizer Nationallizenzen (
Fulltext version: Published version
License (according to publishing contract): Licence according to publishing contract
Departement: Applied Psychology
Organisational Unit: Psychological Institute (PI)
Appears in Collections:Publikationen Angewandte Psychologie

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