Title: Intranasal oxytocin increases positive communication and reduces cortisol levels during couple conflict
Authors : Ditzen, Beate
Schär Gmelch, Marcel
Gabriel, Barbara
Bodenmann, Guy
Ehlert, Ulrike
Heinrichs, Markus
Published in : Biological Psychiatry
Volume(Issue) : 65
Issue : 9
Pages : 728
Pages to: 731
Publisher / Ed. Institution : Elsevier
Issue Date: May-2009
License (according to publishing contract) : Licence according to publishing contract
Type of review: Peer review (Publication)
Language : English
Subjects : Couple conflict; Intranasal oxytocin; Salivary cortisol; Social interaction; Stress
Subject (DDC) : 158: Applied psychology
302: Social interaction
610: Medicine and health
Abstract: Background: In nonhuman mammals, the neuropeptide oxytocin has repeatedly been shown to increase social approach behavior and pair bonding. In particular, central nervous oxytocin reduces behavioral and neuroendocrine responses to social stress and is suggested to mediate the rewarding aspects of attachment in highly social species. However, to date there have been no studies investigating the effects of central oxytocin mechanisms on behavior and physiology in human couple interaction. Methods: In a double-blind placebo-controlled design, 47 heterosexual couples (total n = 94) received oxytocin or placebo intranasally before a standard instructed couple conflict discussion in the laboratory. The conflict session was videotaped and coded for verbal and nonverbal interaction behavior (e.g., eye contact, nonverbal positive behavior, and self-disclosure). Salivary cortisol was repeatedly measured during the experiment. Results: Oxytocin significantly increased positive communication behavior in relation to negative behavior during the couple conflict discussion (F = 4.18, p = .047) and significantly reduced salivary cortisol levels after the conflict compared with placebo (F = 7.14, p = .011). Conclusions: These results are in line with animal studies indicating that central oxytocin facilitates approach and pair bonding behavior. Our findings imply an involvement of oxytocin in couple interaction and close relationships in humans.
Departement: Angewandte Psychologie
Organisational Unit: Institute of Applied Psychology (IAP)
Publication type: Article in scientific Journal
DOI : 10.1016/j.biopsych.2008.10.011
ISSN: 0006-3223
1873-2402
URI: https://digitalcollection.zhaw.ch/handle/11475/5268
Appears in Collections:Publikationen Angewandte Psychologie

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