|Publication type:||Article in scientific journal|
|Type of review:||Peer review (publication)|
|Title:||SENSE-DTI at 3 T|
van Muiswinkel, A.M.C
van Zijl, P.C.M.
|Published in:||Magnetic Resonance in Medicine|
|Publisher / Ed. Institution:||Wiley|
|Subjects:||Anisotropy; Brain; Brain mapping; Diffusion Magnetic Resonance Imaging; Humans; Three-dimensional imaging; Theoretical models|
|Subject (DDC):||616.8: Neurology, diseases of nervous system|
|Abstract:||While holding vast potential, diffusion tensor imaging (DTI) with single-excitation protocols still faces serious challenges. Limited spatial resolution, susceptibility to magnetic field inhomogeneity, and low signal-to-noise ratio (SNR) may be considered the most prominent limitations. It is demonstrated that all of these shortcomings can be effectively mitigated by the transition to parallel imaging technology and high magnetic field strength. Using the sensitivity encoding (SENSE) technique at 3 T, brain DTI was performed in nine healthy volunteers. Despite enhanced field inhomogeneity, parallel acquisition permitted both controlling geometric distortions and enhancing spatial resolution up to 0.8 mm in-plane. Heightened SNR requirements were met in part by high base sensitivity at 3 T. A further significant increase in SNR efficiency was accomplished by SENSE acquisition, exploiting enhanced encoding speed for echo time reduction. Based on the resulting image data, high-resolution tensor mapping is demonstrated.|
|Fulltext version:||Published version|
|License (according to publishing contract):||Licence according to publishing contract|
|Departement:||School of Engineering|
|Appears in Collections:||Publikationen School of Engineering|
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