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Please use this identifier to cite or link to this item: https://doi.org/10.21256/zhaw-30704
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dc.contributor.authorWüster, Wolf-
dc.contributor.authorGebbers, Pit-
dc.contributor.authorRenn, Alois-
dc.contributor.authorBütikofer, Matthias-
dc.contributor.authorRüdiger, Sophie-
dc.contributor.authorRiek, Roland P.-
dc.contributor.authorTorres, Felix-
dc.date.accessioned2024-05-22T12:49:47Z-
dc.date.available2024-05-22T12:49:47Z-
dc.date.issued2024-
dc.identifier.issn2699-0016de_CH
dc.identifier.urihttps://digitalcollection.zhaw.ch/handle/11475/30704-
dc.description.abstractRecent advances in NMR fragment screening use sample illumination to boost NMR sensitivity, reduce measurement time to a few seconds, and reduce sample concentration to a few micromolars. Nevertheless, the absence of a fully automated solution to measure several hundreds of samples with photoinduced hyperpolarization limits the large-scale applicability of the method. We present a setup to couple an optical fiber with a cryogenic probe using the flow-cell accessory port. This setup is compatible with commercially available autosamplers, enabling the fully automated measurement of several hundreds of samples per day.de_CH
dc.language.isoende_CH
dc.publisherCopernicus Publicationsde_CH
dc.relation.ispartofMagnetic Resonancede_CH
dc.rightshttps://creativecommons.org/licenses/by/4.0/de_CH
dc.subjectNuclear magnetic resonance (NMR)de_CH
dc.subjectPhoto-CIDNPde_CH
dc.subjectHyperpolarizationde_CH
dc.subject.ddc530: Physikde_CH
dc.titleLight-coupled cryogenic probes to detect low-micromolar samples and allow for an automated NMR platformde_CH
dc.typeBeitrag in wissenschaftlicher Zeitschriftde_CH
dcterms.typeTextde_CH
zhaw.departementSchool of Engineeringde_CH
zhaw.organisationalunitInstitut für Angewandte Mathematik und Physik (IAMP)de_CH
dc.identifier.doi10.5194/mr-5-61-2024de_CH
dc.identifier.doi10.21256/zhaw-30704-
zhaw.funding.euNode_CH
zhaw.issue1de_CH
zhaw.originated.zhawYesde_CH
zhaw.pages.end67de_CH
zhaw.pages.start61de_CH
zhaw.publication.statuspublishedVersionde_CH
zhaw.volume5de_CH
zhaw.publication.reviewPeer review (Publikation)de_CH
zhaw.funding.zhawOff-the-shelf upgrade to improve drug screening throughput by a factor 30de_CH
zhaw.author.additionalNode_CH
zhaw.display.portraitYesde_CH
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Wüster, W., Gebbers, P., Renn, A., Bütikofer, M., Rüdiger, S., Riek, R. P., & Torres, F. (2024). Light-coupled cryogenic probes to detect low-micromolar samples and allow for an automated NMR platform. Magnetic Resonance, 5(1), 61–67. https://doi.org/10.5194/mr-5-61-2024
Wüster, W. et al. (2024) ‘Light-coupled cryogenic probes to detect low-micromolar samples and allow for an automated NMR platform’, Magnetic Resonance, 5(1), pp. 61–67. Available at: https://doi.org/10.5194/mr-5-61-2024.
W. Wüster et al., “Light-coupled cryogenic probes to detect low-micromolar samples and allow for an automated NMR platform,” Magnetic Resonance, vol. 5, no. 1, pp. 61–67, 2024, doi: 10.5194/mr-5-61-2024.
WÜSTER, Wolf, Pit GEBBERS, Alois RENN, Matthias BÜTIKOFER, Sophie RÜDIGER, Roland P. RIEK und Felix TORRES, 2024. Light-coupled cryogenic probes to detect low-micromolar samples and allow for an automated NMR platform. Magnetic Resonance. 2024. Bd. 5, Nr. 1, S. 61–67. DOI 10.5194/mr-5-61-2024
Wüster, Wolf, Pit Gebbers, Alois Renn, Matthias Bütikofer, Sophie Rüdiger, Roland P. Riek, and Felix Torres. 2024. “Light-Coupled Cryogenic Probes to Detect Low-Micromolar Samples and Allow for an Automated NMR Platform.” Magnetic Resonance 5 (1): 61–67. https://doi.org/10.5194/mr-5-61-2024.
Wüster, Wolf, et al. “Light-Coupled Cryogenic Probes to Detect Low-Micromolar Samples and Allow for an Automated NMR Platform.” Magnetic Resonance, vol. 5, no. 1, 2024, pp. 61–67, https://doi.org/10.5194/mr-5-61-2024.


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