Urinary metabolic biomarker profiling for cancer ciagnosis by terahertz spectroscopy : review and perspective

Abina, Andreja; Korošec, Tjaša; Puc, Uros; Jazbinsek, Mojca; Zidanšek, Aleksander

doi:10.3390/photonics10091051

Please use this identifier to cite or link to this item: https://doi.org/10.21256/zhaw-30169

Publication type:	Article in scientific journal
Type of review:	Peer review (publication)
Title:	Urinary metabolic biomarker profiling for cancer ciagnosis by terahertz spectroscopy : review and perspective
Authors:	Abina, Andreja Korošec, Tjaša Puc, Uros Jazbinsek, Mojca Zidanšek, Aleksander
et. al:	No
DOI:	10.3390/photonics10091051 10.21256/zhaw-30169
Published in:	Photonics
Volume(Issue):	10
Issue:	9
Page(s):	1051
Issue Date:	2023
Publisher / Ed. Institution:	MDPI
ISSN:	2304-6732
Language:	English
Subjects:	THz Photonics; Terahertz spectroscopy; Urinary biomarker; Metabolic biomarker; Cancer diagnostics; Biomolecules; Non-invasive detection; Biomedical detection
Subject (DDC):	616: Internal medicine and diseases 621.3: Electrical, communications, control engineering
Abstract:	In the last decade, terahertz (THz) technologies have been introduced to the detection, identification, and quantification of biomolecules in various biological samples. This review focuses on substances that represent important biomarkers in the urine associated with various cancers and their treatments. From a diagnostic point of view, urine liquid biopsy is particularly important because it allows the non-invasive and rapid collection of large volumes of samples. In this review, the THz spectral responses of substances considered metabolic biomarkers in urine and obtained in previous studies are collected. In addition, the findings from the relatively small number of prior studies that have already been carried out on urine samples are summarised. In this context, we also present the different THz methods used for urine analysis. Finally, a brief discussion is given, presenting perspectives for future research in this field, interpreted based on the results of previous studies. This work provides important information on the further application of THz techniques in biomedicine for detecting and monitoring urinary biomarkers for various diseases, including cancer.
URI:	https://digitalcollection.zhaw.ch/handle/11475/30169
Fulltext version:	Published version
License (according to publishing contract):	CC BY 4.0: Attribution 4.0 International
Departement:	School of Engineering
Organisational Unit:	Institute of Computational Physics (ICP)
Appears in collections:	Publikationen School of Engineering

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Abina, A., Korošec, T., Puc, U., Jazbinsek, M., & Zidanšek, A. (2023). Urinary metabolic biomarker profiling for cancer ciagnosis by terahertz spectroscopy : review and perspective. Photonics, 10(9), 1051. https://doi.org/10.3390/photonics10091051

Abina, A. et al. (2023) ‘Urinary metabolic biomarker profiling for cancer ciagnosis by terahertz spectroscopy : review and perspective’, Photonics, 10(9), p. 1051. Available at: https://doi.org/10.3390/photonics10091051.

A. Abina, T. Korošec, U. Puc, M. Jazbinsek, and A. Zidanšek, “Urinary metabolic biomarker profiling for cancer ciagnosis by terahertz spectroscopy : review and perspective,” Photonics, vol. 10, no. 9, p. 1051, 2023, doi: 10.3390/photonics10091051.

ABINA, Andreja, Tjaša KOROŠEC, Uros PUC, Mojca JAZBINSEK und Aleksander ZIDANŠEK, 2023. Urinary metabolic biomarker profiling for cancer ciagnosis by terahertz spectroscopy : review and perspective. Photonics. 2023. Bd. 10, Nr. 9, S. 1051. DOI 10.3390/photonics10091051

Abina, Andreja, Tjaša Korošec, Uros Puc, Mojca Jazbinsek, and Aleksander Zidanšek. 2023. “Urinary Metabolic Biomarker Profiling for Cancer Ciagnosis by Terahertz Spectroscopy : Review and Perspective.” Photonics 10 (9): 1051. https://doi.org/10.3390/photonics10091051.

Abina, Andreja, et al. “Urinary Metabolic Biomarker Profiling for Cancer Ciagnosis by Terahertz Spectroscopy : Review and Perspective.” Photonics, vol. 10, no. 9, 2023, p. 1051, https://doi.org/10.3390/photonics10091051.