Historical herbal texts from Switzerland : a potential source for plant- derived natural products against SARS-CoV-2

Vahekeni, Nina; Urmann, Corinna; Stehlin, Jonas; Hofer, Niklas; Gmach, Yvonne; Wolfram, Evelyn; Lardos, Andreas

Publication type:	Conference poster
Type of review:	Peer review (abstract)
Title:	Historical herbal texts from Switzerland : a potential source for plant- derived natural products against SARS-CoV-2
Authors:	Vahekeni, Nina Urmann, Corinna Stehlin, Jonas Hofer, Niklas Gmach, Yvonne Wolfram, Evelyn Lardos, Andreas
et. al:	No
Published in:	Planta Medica
Volume(Issue):	89
Issue:	14
Page(s):	1422
Conference details:	71st International Congress and Annual Meeting of the Society for Medicinal Plant and Natural Product Research (GA), Dublin, Ireland, 2–5 July 2023
Issue Date:	2023
Publisher / Ed. Institution:	Thieme
ISSN:	0032-0943 1439-0221
Language:	English
Subjects:	Schweiz; Arzneimittel; 16. Jahrhunder; Covid; Phytopharmakologie; Heilpflanze
Subject (DDC):	580: Plants (Botany) 615: Pharmacology and therapeutics
Abstract:	In search for more effective prophylactic and curative therapeutics against SARS-CoV-2, an ethnopharmcological approach was used to select 20 plants described in the “Arzneibuch von Hallwyl” (ABvH), an influential recipe text from 16th century Switzerland. Plants were selected based on specific historical uses possibly linked with the treatment of microbial or viral infections as well as inflammatory conditions. For each plant candidate, aqueous and hydroethanolic extracts have been produced, respectively. The prophylactic activity of extracts against SARS-CoV-2 was assessed using the CellTiter-Glo Luminescent Cell Viability Assay upon viral infection in vitro. Four plants showed promising activity; among them Sambucus nigra L. (leaves) and Artemisia vulgaris L. (aerial parts) showed an anti-SARS-CoV-2 potential both with an activity of≤33.3 µg/mL for their hydroethanolic extract. The findings confirm the historical traditional use in the area of infectious diseases. Accordingly, this study shows supportive evidence that an ethnopharmacological approach combined with robust in vitro methods effectively enables to screen for promising antiviral plant extracts against SARS-CoV-2.
URI:	https://www.thieme-connect.com/products/ejournals/abstract/10.1055/s-0043-1774265 https://digitalcollection.zhaw.ch/handle/11475/29926
Fulltext version:	Published version
License (according to publishing contract):	Licence according to publishing contract
Departement:	Life Sciences and Facility Management
Organisational Unit:	Institute of Chemistry and Biotechnology (ICBT)
Appears in collections:	Publikationen Life Sciences und Facility Management

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Vahekeni, N., Urmann, C., Stehlin, J., Hofer, N., Gmach, Y., Wolfram, E., & Lardos, A. (2023). Historical herbal texts from Switzerland : a potential source for plant- derived natural products against SARS-CoV-2 [Conference poster]. Planta Medica, 89(14), 1422. https://www.thieme-connect.com/products/ejournals/abstract/10.1055/s-0043-1774265

Vahekeni, N. et al. (2023) ‘Historical herbal texts from Switzerland : a potential source for plant- derived natural products against SARS-CoV-2’, in Planta Medica. Thieme, p. 1422. Available at: https://www.thieme-connect.com/products/ejournals/abstract/10.1055/s-0043-1774265.

N. Vahekeni et al., “Historical herbal texts from Switzerland : a potential source for plant- derived natural products against SARS-CoV-2,” in Planta Medica, 2023, vol. 89, no. 14, p. 1422. [Online]. Available: https://www.thieme-connect.com/products/ejournals/abstract/10.1055/s-0043-1774265

VAHEKENI, Nina, Corinna URMANN, Jonas STEHLIN, Niklas HOFER, Yvonne GMACH, Evelyn WOLFRAM und Andreas LARDOS, 2023. Historical herbal texts from Switzerland : a potential source for plant- derived natural products against SARS-CoV-2. In: Planta Medica [online]. Conference poster. Thieme. 2023. S. 1422. Verfügbar unter: https://www.thieme-connect.com/products/ejournals/abstract/10.1055/s-0043-1774265

Vahekeni, Nina, Corinna Urmann, Jonas Stehlin, Niklas Hofer, Yvonne Gmach, Evelyn Wolfram, and Andreas Lardos. 2023. “Historical Herbal Texts from Switzerland : A Potential Source for Plant- Derived Natural Products against SARS-CoV-2.” Conference poster. In Planta Medica, 89:1422. Thieme. https://www.thieme-connect.com/products/ejournals/abstract/10.1055/s-0043-1774265.

Vahekeni, Nina, et al. “Historical Herbal Texts from Switzerland : A Potential Source for Plant- Derived Natural Products against SARS-CoV-2.” Planta Medica, vol. 89, no. 14, Thieme, 2023, p. 1422, https://www.thieme-connect.com/products/ejournals/abstract/10.1055/s-0043-1774265.