Publication type: Article in scientific journal
Type of review: Peer review (publication)
Title: Suicidality emerging from rapid Venlafaxine discontinuation
Authors: Kostic, Milutin
Plöderl, Martin
Hengartner, Michael
Buzejic, Jelena
et. al: No
DOI: 10.4088/JCP.23cr14930
Published in: The Journal of Clinical Psychiatry
Volume(Issue): 85
Issue: 1
Page(s): 23cr14930
Issue Date: 2024
Publisher / Ed. Institution: Physicians Postgraduate Press
ISSN: 0160-6689
1555-2101
Language: English
Subject (DDC): 615: Pharmacology and therapeutics
616.8: Neurology, diseases of nervous system
Abstract: There is ongoing controversy about suicide risk associated with antidepressant use, but much less is known about suicide risk related to discontinuation of antidepressants. Antidepressant withdrawal syndrome (AWS) can be a burdensome syndrome, with well-known symptoms. One possible explanation for this condition is the oppositional model of tolerance. Some study results are suggestive that suicidality can be part of AWS, although the data are still inconclusive. We are aware of only 3 case reports of suicidal behavior with antidepressant discontinuation, which occurred after discontinuation of paroxetine, venlafaxine, and escitalopram. In this case report, we present a patient without a history of suicidal crisis who, in the span of 6 months, experienced 2 suicidal crises, each occurring directly following rapid discontinuation of venlafaxine. Both crises subsided with reintroduction of the drug.
URI: https://digitalcollection.zhaw.ch/handle/11475/29663
Fulltext version: Published version
License (according to publishing contract): Licence according to publishing contract
Departement: Applied Psychology
Organisational Unit: Psychological Institute (PI)
Appears in collections:Publikationen Angewandte Psychologie

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Kostic, M., Plöderl, M., Hengartner, M., & Buzejic, J. (2024). Suicidality emerging from rapid Venlafaxine discontinuation. The Journal of Clinical Psychiatry, 85(1), 23cr14930. https://doi.org/10.4088/JCP.23cr14930
Kostic, M. et al. (2024) ‘Suicidality emerging from rapid Venlafaxine discontinuation’, The Journal of Clinical Psychiatry, 85(1), p. 23cr14930. Available at: https://doi.org/10.4088/JCP.23cr14930.
M. Kostic, M. Plöderl, M. Hengartner, and J. Buzejic, “Suicidality emerging from rapid Venlafaxine discontinuation,” The Journal of Clinical Psychiatry, vol. 85, no. 1, p. 23cr14930, 2024, doi: 10.4088/JCP.23cr14930.
KOSTIC, Milutin, Martin PLÖDERL, Michael HENGARTNER und Jelena BUZEJIC, 2024. Suicidality emerging from rapid Venlafaxine discontinuation. The Journal of Clinical Psychiatry. 2024. Bd. 85, Nr. 1, S. 23cr14930. DOI 10.4088/JCP.23cr14930
Kostic, Milutin, Martin Plöderl, Michael Hengartner, and Jelena Buzejic. 2024. “Suicidality Emerging from Rapid Venlafaxine Discontinuation.” The Journal of Clinical Psychiatry 85 (1): 23cr14930. https://doi.org/10.4088/JCP.23cr14930.
Kostic, Milutin, et al. “Suicidality Emerging from Rapid Venlafaxine Discontinuation.” The Journal of Clinical Psychiatry, vol. 85, no. 1, 2024, p. 23cr14930, https://doi.org/10.4088/JCP.23cr14930.


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