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dc.contributor.authorBuller, R.-
dc.contributor.authorLutz, S.-
dc.contributor.authorKazlauskas, R. J.-
dc.contributor.authorSnajdrova, R.-
dc.contributor.authorMoore, J. C.-
dc.contributor.authorBornscheuer, U. T.-
dc.date.accessioned2024-01-04T12:54:25Z-
dc.date.available2024-01-04T12:54:25Z-
dc.date.issued2023-11-24-
dc.identifier.issn0036-8075de_CH
dc.identifier.issn1095-9203de_CH
dc.identifier.urihttps://digitalcollection.zhaw.ch/handle/11475/29457-
dc.description.abstractBiocatalysis harnesses enzymes to make valuable products. This green technology is used in countless applications from bench scale to industrial production and allows practitioners to access complex organic molecules, often with fewer synthetic steps and reduced waste. The last decade has seen an explosion in the development of experimental and computational tools to tailor enzymatic properties, equipping enzyme engineers with the ability to create biocatalysts that perform reactions not present in nature. By using (chemo)-enzymatic synthesis routes or orchestrating intricate enzyme cascades, scientists can synthesize elaborate targets ranging from DNA and complex pharmaceuticals to starch made in vitro from CO2-derived methanol. In addition, new chemistries have emerged through the combination of biocatalysis with transition metal catalysis, photocatalysis, and electrocatalysis. This review highlights recent key developments, identifies current limitations, and provides a future prospect for this rapidly developing technology.de_CH
dc.language.isoende_CH
dc.publisherAmerican Association for the Advancement of Sciencede_CH
dc.relation.ispartofSciencede_CH
dc.rightsLicence according to publishing contractde_CH
dc.subjectMethanolde_CH
dc.subjectTechnologyde_CH
dc.subjectSubstrate specificityde_CH
dc.subjectBiocatalysisde_CH
dc.subjectEnzymede_CH
dc.subjectProtein engineeringde_CH
dc.subject.ddc660.6: Biotechnologiede_CH
dc.titleFrom nature to industry : harnessing enzymes for biocatalysisde_CH
dc.typeBeitrag in wissenschaftlicher Zeitschriftde_CH
dcterms.typeTextde_CH
zhaw.departementLife Sciences und Facility Managementde_CH
zhaw.organisationalunitInstitut für Chemie und Biotechnologie (ICBT)de_CH
dc.identifier.doi10.1126/science.adh8615de_CH
dc.identifier.pmid37995253de_CH
zhaw.funding.euNode_CH
zhaw.issue6673de_CH
zhaw.originated.zhawYesde_CH
zhaw.pages.starteadh8615de_CH
zhaw.publication.statuspublishedVersionde_CH
zhaw.volume382de_CH
zhaw.publication.reviewPeer review (Publikation)de_CH
zhaw.funding.snf180544de_CH
zhaw.webfeedBiokatalysede_CH
zhaw.author.additionalNode_CH
zhaw.display.portraitYesde_CH
Appears in collections:Publikationen Life Sciences und Facility Management

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Buller, R., Lutz, S., Kazlauskas, R. J., Snajdrova, R., Moore, J. C., & Bornscheuer, U. T. (2023). From nature to industry : harnessing enzymes for biocatalysis. Science, 382(6673), eadh8615. https://doi.org/10.1126/science.adh8615
Buller, R. et al. (2023) ‘From nature to industry : harnessing enzymes for biocatalysis’, Science, 382(6673), p. eadh8615. Available at: https://doi.org/10.1126/science.adh8615.
R. Buller, S. Lutz, R. J. Kazlauskas, R. Snajdrova, J. C. Moore, and U. T. Bornscheuer, “From nature to industry : harnessing enzymes for biocatalysis,” Science, vol. 382, no. 6673, p. eadh8615, Nov. 2023, doi: 10.1126/science.adh8615.
BULLER, R., S. LUTZ, R. J. KAZLAUSKAS, R. SNAJDROVA, J. C. MOORE und U. T. BORNSCHEUER, 2023. From nature to industry : harnessing enzymes for biocatalysis. Science. 24 November 2023. Bd. 382, Nr. 6673, S. eadh8615. DOI 10.1126/science.adh8615
Buller, R., S. Lutz, R. J. Kazlauskas, R. Snajdrova, J. C. Moore, and U. T. Bornscheuer. 2023. “From Nature to Industry : Harnessing Enzymes for Biocatalysis.” Science 382 (6673): eadh8615. https://doi.org/10.1126/science.adh8615.
Buller, R., et al. “From Nature to Industry : Harnessing Enzymes for Biocatalysis.” Science, vol. 382, no. 6673, Nov. 2023, p. eadh8615, https://doi.org/10.1126/science.adh8615.


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