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https://doi.org/10.21256/zhaw-28531| Publication type: | Article in scientific journal |
| Type of review: | Peer review (publication) |
| Title: | Observational studies of antidepressant use and suicide risk are selectively published in psychiatric journals |
| Authors: | Plöderl, Martin Amendola, Simone Hengartner, Michael P. |
| et. al: | No |
| DOI: | 10.1016/j.jclinepi.2023.07.015 10.21256/zhaw-28531 |
| Published in: | Journal of Clinical Epidemiology |
| Volume(Issue): | 162 |
| Page(s): | 10 |
| Pages to: | 18 |
| Issue Date: | 5-Aug-2023 |
| Publisher / Ed. Institution: | Elsevier |
| ISSN: | 0895-4356 1878-5921 |
| Language: | English |
| Subject (DDC): | 000: Generalities and science |
| Abstract: | Objectives: To investigate if observational studies showing favorable results for antidepressants on suicidal behavior (reduced risk) are preferably and more easily published in psychiatric journals and cited more often, compared to studies with unfavorable results (increased risk). Study design and setting: Prespecified secondary analysis including 27 original studies selected through a systematic review of observational studies reporting associations between use of newer antidepressant drugs and suicide risk. Results: Independent of study quality, studies reporting favorable results were more frequently published in psychiatric than non-psychiatric journals and were more often conducted by lead-authors with financial conflicts of interest (fCOI). Within psychiatric journals, lead-authors with fCOI published in journals with higher impact factor and ranking. Within psychiatric journals, favorability of results also correlated with citation frequency, impact factor, and journal ranking, but these associations became weaker and inconclusive after adjusting for study quality. Results for ease of publishing were inconclusive. Conclusion: Studies reporting unfavorable results (increased suicide risk with antidepressant-exposure) are less likely published in psychiatric journals. Lead-authors with fCOI report more favorable results and their studies are published in the most prestigious psychiatric journals. This may create a biased evidence-base and an unbalanced dissemination and appraisal of findings within psychiatry. |
| URI: | https://digitalcollection.zhaw.ch/handle/11475/28531 |
| Related research data: | https://osf.io/avhg4/ |
| Fulltext version: | Published version |
| License (according to publishing contract): | CC BY 4.0: Attribution 4.0 International |
| Departement: | Applied Psychology |
| Organisational Unit: | Psychological Institute (PI) |
| Appears in collections: | Publikationen Angewandte Psychologie |
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| File | Description | Size | Format | |
|---|---|---|---|---|
| 2023_Ploederl-etal_Observational-studies-of-antidepressant-use-and-suicide-risk.pdf | 330.86 kB | Adobe PDF |  View/Open |
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Plöderl, M., Amendola, S., & Hengartner, M. P. (2023). Observational studies of antidepressant use and suicide risk are selectively published in psychiatric journals. Journal of Clinical Epidemiology, 162, 10–18. https://doi.org/10.1016/j.jclinepi.2023.07.015
Plöderl, M., Amendola, S. and Hengartner, M.P. (2023) ‘Observational studies of antidepressant use and suicide risk are selectively published in psychiatric journals’, Journal of Clinical Epidemiology, 162, pp. 10–18. Available at: https://doi.org/10.1016/j.jclinepi.2023.07.015.
M. Plöderl, S. Amendola, and M. P. Hengartner, “Observational studies of antidepressant use and suicide risk are selectively published in psychiatric journals,” Journal of Clinical Epidemiology, vol. 162, pp. 10–18, Aug. 2023, doi: 10.1016/j.jclinepi.2023.07.015.
PLÖDERL, Martin, Simone AMENDOLA und Michael P. HENGARTNER, 2023. Observational studies of antidepressant use and suicide risk are selectively published in psychiatric journals. Journal of Clinical Epidemiology. 5 August 2023. Bd. 162, S. 10–18. DOI 10.1016/j.jclinepi.2023.07.015
Plöderl, Martin, Simone Amendola, and Michael P. Hengartner. 2023. “Observational Studies of Antidepressant Use and Suicide Risk Are Selectively Published in Psychiatric Journals.” Journal of Clinical Epidemiology 162 (August): 10–18. https://doi.org/10.1016/j.jclinepi.2023.07.015.
Plöderl, Martin, et al. “Observational Studies of Antidepressant Use and Suicide Risk Are Selectively Published in Psychiatric Journals.” Journal of Clinical Epidemiology, vol. 162, Aug. 2023, pp. 10–18, https://doi.org/10.1016/j.jclinepi.2023.07.015.
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