Paracelsus' legacy in the faunal realm : drugs deriving from animal toxins

Fischer, Thomas; Riedl, Rainer

doi:10.1016/j.drudis.2021.10.003

Please use this identifier to cite or link to this item: https://doi.org/10.21256/zhaw-26688

Publication type:	Article in scientific journal
Type of review:	Peer review (publication)
Title:	Paracelsus' legacy in the faunal realm : drugs deriving from animal toxins
Authors:	Fischer, Thomas Riedl, Rainer
et. al:	No
DOI:	10.1016/j.drudis.2021.10.003 10.21256/zhaw-26688
Published in:	Drug Discovery Today
Volume(Issue):	27
Issue:	2
Page(s):	567
Pages to:	575
Issue Date:	Feb-2022
Publisher / Ed. Institution:	Elsevier
ISSN:	1359-6446 1878-5832
Language:	English
Subjects:	Animal toxin; Drug discovery; Medicinal chemistry; Natural product; Peptide; Venom; Animal; Toxin, biological; Venom
Subject (DDC):	615: Pharmacology and therapeutics
Abstract:	Given the vast number of venomous and poisonous animals, it is surprising that only relatively few animal-derived toxins have been explored and made their way into marketed drugs or are being investigated in ongoing clinical trials. In this review, we highlight marketed drugs deriving from animal toxins as well as ongoing clinical trials and preclinical investigations in the field. We emphasize that more attention should be paid to the rich supply of candidates that nature provides as valuable starting points for addressing serious unmet medical needs.
URI:	https://digitalcollection.zhaw.ch/handle/11475/26688
Fulltext version:	Published version
License (according to publishing contract):	CC BY-NC-ND 4.0: Attribution - Non commercial - No derivatives 4.0 International
Departement:	Life Sciences and Facility Management
Organisational Unit:	Institute of Chemistry and Biotechnology (ICBT)
Appears in collections:	Publikationen Life Sciences und Facility Management

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