Simultaneous determination of enthalpy of mixing and reaction using milli-scale continuous flow calorimetry

Steinemann, Finn Lorenz; Rütti, David Paul; Moser, Marlies; Georg, Alain; Meier, Daniel Matthias

doi:10.1007/s41981-022-00237-x

Please use this identifier to cite or link to this item: https://doi.org/10.21256/zhaw-25456

Publication type:	Article in scientific journal
Type of review:	Peer review (publication)
Title:	Simultaneous determination of enthalpy of mixing and reaction using milli-scale continuous flow calorimetry
Authors:	Steinemann, Finn Lorenz Rütti, David Paul Moser, Marlies Georg, Alain Meier, Daniel Matthias
et. al:	No
DOI:	10.1007/s41981-022-00237-x 10.21256/zhaw-25456
Published in:	Journal of Flow Chemistry
Volume(Issue):	12
Issue:	4
Page(s):	389
Pages to:	396
Issue Date:	27-Jul-2022
Publisher / Ed. Institution:	Springer
ISSN:	2062-249X 2063-0212
Language:	English
Subjects:	Continuous flow calorimetry; Scale-up; Polytropic reaction; Calorimetry; Heat of reaction; Hydrolysis of acetic anhydride; Process development
Subject (DDC):	540: Chemistry
Abstract:	A simultaneous determination of the enthalpy of mixing and reaction in a scalable continuous milli-scale flow calorimeter is investigated. As obtained calorimetric data is pivotal for the safety assessment of chemical reactions and processes. The acid-catalysed selective, homogeneous hydrolysis of acetic anhydride with half-lives from a few seconds to a few minutes is investigated as a model reaction. For the enthalpy of mixing 7.2 ± 2.8 kJ/mol and for the enthalpy of reaction −60.8 ± 2.5 kJ/mol were determined. For reactions that show complete conversion in the continuous reactor, a technique is introduced to further improve the accuracy of the reaction enthalpy determination. Thereby, the resolution of the observed temperature profile is increased by measuring the profile at different flow rates. Applying this procedure, the reaction enthalpy of −62.5 kJ/mol was determined which is in good agreement with literature values for this model reaction.
URI:	https://digitalcollection.zhaw.ch/handle/11475/25456
Fulltext version:	Published version
License (according to publishing contract):	CC BY 4.0: Attribution 4.0 International
Departement:	School of Engineering
Organisational Unit:	Institute of Materials and Process Engineering (IMPE)
Published as part of the ZHAW project:	Entwicklung eines experimentbasierten Designtools für kontinuierliche Reaktoren
Appears in collections:	Publikationen School of Engineering

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Steinemann, F. L., Rütti, D. P., Moser, M., Georg, A., & Meier, D. M. (2022). Simultaneous determination of enthalpy of mixing and reaction using milli-scale continuous flow calorimetry. Journal of Flow Chemistry, 12(4), 389–396. https://doi.org/10.1007/s41981-022-00237-x

Steinemann, F.L. et al. (2022) ‘Simultaneous determination of enthalpy of mixing and reaction using milli-scale continuous flow calorimetry’, Journal of Flow Chemistry, 12(4), pp. 389–396. Available at: https://doi.org/10.1007/s41981-022-00237-x.

F. L. Steinemann, D. P. Rütti, M. Moser, A. Georg, and D. M. Meier, “Simultaneous determination of enthalpy of mixing and reaction using milli-scale continuous flow calorimetry,” Journal of Flow Chemistry, vol. 12, no. 4, pp. 389–396, Jul. 2022, doi: 10.1007/s41981-022-00237-x.

STEINEMANN, Finn Lorenz, David Paul RÜTTI, Marlies MOSER, Alain GEORG und Daniel Matthias MEIER, 2022. Simultaneous determination of enthalpy of mixing and reaction using milli-scale continuous flow calorimetry. Journal of Flow Chemistry. 27 Juli 2022. Bd. 12, Nr. 4, S. 389–396. DOI 10.1007/s41981-022-00237-x

Steinemann, Finn Lorenz, David Paul Rütti, Marlies Moser, Alain Georg, and Daniel Matthias Meier. 2022. “Simultaneous Determination of Enthalpy of Mixing and Reaction Using Milli-Scale Continuous Flow Calorimetry.” Journal of Flow Chemistry 12 (4): 389–96. https://doi.org/10.1007/s41981-022-00237-x.

Steinemann, Finn Lorenz, et al. “Simultaneous Determination of Enthalpy of Mixing and Reaction Using Milli-Scale Continuous Flow Calorimetry.” Journal of Flow Chemistry, vol. 12, no. 4, July 2022, pp. 389–96, https://doi.org/10.1007/s41981-022-00237-x.