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|Publication type:||Article in scientific journal|
|Type of review:||No review|
|Title:||Cross-industrial applications of organotypic models|
|Authors:||Kopanska, Katarzyna S|
|Published in:||ALTEX - Alternatives to Animal Experimentation|
|Publisher / Ed. Institution:||Springer|
|Subjects:||Microphysiological system; Cross-sectoral collaboration; 3D cell culture; Drug development; Human-relevant test system; Alternative method; Lab-On-A-Chip device; 3Rs principle; Biofabrication|
|Subject (DDC):||610.28: Biomedicine, biomedical engineering|
|Abstract:||Recent advances in microphysiological systems (MPS) promise a global paradigm shift in drug development, diagnostics, disease prevention, and therapy. The expectation is that these systems will model healthy and various diseased stages and disease progression to predict toxicity, immunogenicity, ADME profiles, and treatment efficacies. MPS will provide unprecedented human-like physiological properties of in vitro models, enabling their routine application in the pharma industry and thus reducing drug development costs by lowering the attrition rate of compounds. We showcased MPS application diversity across different industries during the TEDD Annual Meeting on 14th October 2021 in Wädenswil, Switzerland. The goal was to promote cross-sectoral collaboration of academia and industry to further pave the way for developing next-generation MPS based on 3D cell culture, organoid, and organ-on-chip technology and their widespread exploitation. To enable visionary projects and radical innovations, we covered multidisciplinary fields and connected different industry sectors, like pharma, medtech, biotech, cosmetics, diagnostics, fragrances, and food, with each other.|
|Fulltext version:||Published version|
|License (according to publishing contract):||CC BY 4.0: Attribution 4.0 International|
|Departement:||Life Sciences and Facility Management|
|Organisational Unit:||Institute of Chemistry and Biotechnology (ICBT)|
|Published as part of the ZHAW project:||3D Gewebe TEDD|
|Appears in collections:||Publikationen Life Sciences und Facility Management|
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|2022_Kopanska-Rimann_Cross-industrial-applications-organotypic-models.pdf||1.03 MB||Adobe PDF|
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Kopanska, K. S., & Rimann, M. (2022). Cross-industrial applications of organotypic models. ALTEX - Alternatives to Animal Experimentation, 39(1), 155–158. https://doi.org/10.14573/altex.2112202
Kopanska, K.S. and Rimann, M. (2022) ‘Cross-industrial applications of organotypic models’, ALTEX - Alternatives to Animal Experimentation, 39(1), pp. 155–158. Available at: https://doi.org/10.14573/altex.2112202.
K. S. Kopanska and M. Rimann, “Cross-industrial applications of organotypic models,” ALTEX - Alternatives to Animal Experimentation, vol. 39, no. 1, pp. 155–158, 2022, doi: 10.14573/altex.2112202.
Kopanska, Katarzyna S., and Markus Rimann. “Cross-Industrial Applications of Organotypic Models.” ALTEX - Alternatives to Animal Experimentation, vol. 39, no. 1, 2022, pp. 155–58, https://doi.org/10.14573/altex.2112202.
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