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Publication type: Article in scientific journal
Type of review: Peer review (publication)
Title: New perspectives in oral peptide delivery
Authors: Zizzari, Alessandra Tania
Pliatsika, Dimanthi
Gall, Flavio
Fischer, Thomas
Riedl, Rainer
et. al: No
DOI: 10.1016/j.drudis.2021.01.020
Published in: Drug Discovery Today
Volume(Issue): 26
Issue: 4
Page(s): 1097
Pages to: 1105
Issue Date: 23-Jan-2021
Publisher / Ed. Institution: Elsevier
ISSN: 1878-5832
Language: English
Subject (DDC): 615: Pharmacology and therapeutics
Abstract: Owing to their structural diversity, peptides are a unique source of innovative active ingredients. However, their development has been challenging because of their disadvantageous pharmacokinetic (PK) properties. Over the past decade, many attempts have been made to improve the oral bioavailability of peptide drugs. In this review, we highlight the most recent and promising techniques aimed at the improvement of the oral bioavailability of peptides. The most recent findings will influence future approaches of pharmaceutical companies in the development of new, more efficient, and safer orally delivered peptides.
Fulltext version: Published version
License (according to publishing contract): CC BY-NC-ND 4.0: Attribution - Non commercial - No derivatives 4.0 International
Departement: Life Sciences and Facility Management
Organisational Unit: Institute of Chemistry and Biotechnology (ICBT)
Appears in collections:Publikationen Life Sciences und Facility Management

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Zizzari, A. T., Pliatsika, D., Gall, F., Fischer, T., & Riedl, R. (2021). New perspectives in oral peptide delivery. Drug Discovery Today, 26(4), 1097–1105.
Zizzari, A.T. et al. (2021) ‘New perspectives in oral peptide delivery’, Drug Discovery Today, 26(4), pp. 1097–1105. Available at:
A. T. Zizzari, D. Pliatsika, F. Gall, T. Fischer, and R. Riedl, “New perspectives in oral peptide delivery,” Drug Discovery Today, vol. 26, no. 4, pp. 1097–1105, Jan. 2021, doi: 10.1016/j.drudis.2021.01.020.
ZIZZARI, Alessandra Tania, Dimanthi PLIATSIKA, Flavio GALL, Thomas FISCHER und Rainer RIEDL, 2021. New perspectives in oral peptide delivery. Drug Discovery Today. 23 Januar 2021. Bd. 26, Nr. 4, S. 1097–1105. DOI 10.1016/j.drudis.2021.01.020
Zizzari, Alessandra Tania, Dimanthi Pliatsika, Flavio Gall, Thomas Fischer, and Rainer Riedl. 2021. “New Perspectives in Oral Peptide Delivery.” Drug Discovery Today 26 (4): 1097–1105.
Zizzari, Alessandra Tania, et al. “New Perspectives in Oral Peptide Delivery.” Drug Discovery Today, vol. 26, no. 4, Jan. 2021, pp. 1097–105,

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