Please use this identifier to cite or link to this item: https://doi.org/10.21256/zhaw-21844
Publication type: Article in scientific journal
Type of review: Peer review (publication)
Title: New perspectives in oral peptide delivery
Authors: Zizzari, Alessandra Tania
Pliatsika, Dimanthi
Gall, Flavio
Fischer, Thomas
Riedl, Rainer
et. al: No
DOI: 10.1016/j.drudis.2021.01.020
10.21256/zhaw-21844
Published in: Drug discovery today
Issue Date: 23-Jan-2021
Publisher / Ed. Institution: Elsevier
ISSN: 1878-5832
Language: English
Subject (DDC): 615: Pharmacology and therapeutics
Abstract: Owing to their structural diversity, peptides are a unique source of innovative active ingredients. However, their development has been challenging because of their disadvantageous pharmacokinetic (PK) properties. Over the past decade, many attempts have been made to improve the oral bioavailability of peptide drugs. In this review, we highlight the most recent and promising techniques aimed at the improvement of the oral bioavailability of peptides. The most recent findings will influence future approaches of pharmaceutical companies in the development of new, more efficient, and safer orally delivered peptides.
URI: https://digitalcollection.zhaw.ch/handle/11475/21844
Fulltext version: Published version
License (according to publishing contract): CC BY-NC-ND 4.0: Attribution - Non commercial - No derivatives 4.0 International
Departement: Life Sciences and Facility Management
Organisational Unit: Institute of Chemistry and Biotechnology (ICBT)
Appears in collections:Publikationen Life Sciences und Facility Management

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