A comparative study of silver nanoparticle dissolution under physiological conditions

Steinmetz, Lukas; Geers, Christoph; Balog, Sandor; Bonmarin, Mathias; Rodriguez-Lorenzo, Laura; Taladriz-Blanco, Patricia; Rothen-Rutishauser, Barbara; Petri-Fink, Alke

doi:10.1039/D0NA00733A

Please use this identifier to cite or link to this item: https://doi.org/10.21256/zhaw-21009

Publication type:	Article in scientific journal
Type of review:	Peer review (publication)
Title:	A comparative study of silver nanoparticle dissolution under physiological conditions
Authors:	Steinmetz, Lukas Geers, Christoph Balog, Sandor Bonmarin, Mathias Rodriguez-Lorenzo, Laura Taladriz-Blanco, Patricia Rothen-Rutishauser, Barbara Petri-Fink, Alke
et. al:	No
DOI:	10.1039/D0NA00733A 10.21256/zhaw-21009
Published in:	Nanoscale Advances
Volume(Issue):	2
Issue:	12
Page(s):	5760
Pages to:	5768
Issue Date:	Oct-2020
Publisher / Ed. Institution:	Royal Society of Chemistry
ISSN:	2516-0230
Language:	English
Subject (DDC):	540: Chemistry
Abstract:	Upon dissolution of silver nanoparticles, silver ions are released into the environment, which are known to induce adverse effects. However, since dissolution studies are predominantly performed in water and/or at room temperature, the effects of biological media and physiologically relevant temperature on the dissolution rate are not considered. Here, we investigate silver nanoparticle dissolution trends based on their plasmonic properties under biologically relevant conditions, i.e. in biological media at 37 °C over a period of 24 h. The studied nanoparticles, surface-functionalized with polyvinylpyrrolidone, beta-cyclodextrin/polyvinylpyrrolidone, and starch/polyvinylpyrrolidone, were analysed by UV-Vis spectroscopy, lock-in thermography and depolarized dynamic light scattering to evaluate the influence of these coatings on silver nanoparticle dissolution. Transmission electron microscopy was employed to visualize the reduction of the nanoparticle core diameters. Consequently, the advantages and limitations of these analytical techniques are discussed. To assess the effects of temperature on the degree of dissolution, the results of experiments performed at biological temperature were compared to those obtained at room temperature. Dissolution is often enhanced at elevated temperatures, but has to be determined individually for every specific condition. Furthermore, we evaluated potential nanoparticle aggregation. Our results highlight that additional surface coatings do not necessarily hinder the dissolution or aggregation of silver nanoparticles.
URI:	https://digitalcollection.zhaw.ch/handle/11475/21009
Fulltext version:	Published version
License (according to publishing contract):	CC BY 3.0: Attribution 3.0 Unported
Departement:	School of Engineering
Organisational Unit:	Institute of Computational Physics (ICP)
Appears in collections:	Publikationen School of Engineering

Files in This Item:

File	Description	Size	Format
2020_Bonmarie_A_comparative_study_of_silver_nanoparticle_dissolution_under_physiological_conditions.pdf		640.4 kB	Adobe PDF	View/Open

Show full item record

Steinmetz, L., Geers, C., Balog, S., Bonmarin, M., Rodriguez-Lorenzo, L., Taladriz-Blanco, P., Rothen-Rutishauser, B., & Petri-Fink, A. (2020). A comparative study of silver nanoparticle dissolution under physiological conditions. Nanoscale Advances, 2(12), 5760–5768. https://doi.org/10.1039/D0NA00733A

Steinmetz, L. et al. (2020) ‘A comparative study of silver nanoparticle dissolution under physiological conditions’, Nanoscale Advances, 2(12), pp. 5760–5768. Available at: https://doi.org/10.1039/D0NA00733A.

L. Steinmetz et al., “A comparative study of silver nanoparticle dissolution under physiological conditions,” Nanoscale Advances, vol. 2, no. 12, pp. 5760–5768, Oct. 2020, doi: 10.1039/D0NA00733A.

STEINMETZ, Lukas, Christoph GEERS, Sandor BALOG, Mathias BONMARIN, Laura RODRIGUEZ-LORENZO, Patricia TALADRIZ-BLANCO, Barbara ROTHEN-RUTISHAUSER und Alke PETRI-FINK, 2020. A comparative study of silver nanoparticle dissolution under physiological conditions. Nanoscale Advances. Oktober 2020. Bd. 2, Nr. 12, S. 5760–5768. DOI 10.1039/D0NA00733A

Steinmetz, Lukas, Christoph Geers, Sandor Balog, Mathias Bonmarin, Laura Rodriguez-Lorenzo, Patricia Taladriz-Blanco, Barbara Rothen-Rutishauser, and Alke Petri-Fink. 2020. “A Comparative Study of Silver Nanoparticle Dissolution under Physiological Conditions.” Nanoscale Advances 2 (12): 5760–68. https://doi.org/10.1039/D0NA00733A.

Steinmetz, Lukas, et al. “A Comparative Study of Silver Nanoparticle Dissolution under Physiological Conditions.” Nanoscale Advances, vol. 2, no. 12, Oct. 2020, pp. 5760–68, https://doi.org/10.1039/D0NA00733A.