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Title: Paclitaxel and baccatin III production induced by methyl jasmonate in free and immobilized cells of Taxus baccata
Authors : Bonfill, M.
Bentebibel, S.
Moyano, E.
Palazón, J.
Cusidó, R. M.
Eibl-Schindler, Regine
Piñol, M. T.
Published in : Biologia Plantarum : Journal for Experimental Botany
Volume(Issue) : 51
Issue : 4
Pages : 647
Pages to: 652
Publisher / Ed. Institution : Springer Netherlands
Issue Date: 2007
License (according to publishing contract) : Licence according to publishing contract
Type of review: Peer review (Publication)
Language : English
Subject (DDC) : 660.6: Biotechnology
Abstract: The effects of 100 and 200 µM methyl jasmonate (MJA) on cell proliferation and paclitaxel and baccatin III production were investigated in free and alginate immobilized cells of Taxus baccata growing in a selected product formation culture medium. The greatest accumulation of paclitaxel (13.20 mg dm−3) and baccatin III (4.62 mg dm−3) occurred when 100 µM MJA was added to the culture medium of cells entrapped using a 1.5 and 2.5 % alginate solution. The effects of different treatments on the viability of cultured cells and their capacity to excrete both taxanes into the surrounding medium were considered. 
Further description : Erworben im Rahmen der Schweizer Nationallizenzen (
Departement: Life Sciences und Facility Management
Publication type: Article in scientific Journal
DOI : 10.1007/s10535-007-0137-2
ISSN: 0006-3134
Restricted until : 2013-01-01
Appears in Collections:Publikationen Life Sciences und Facility Management

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