Paclitaxel and baccatin III production induced by methyl jasmonate in free and immobilized cells of Taxus baccata

Bonfill, M.; Bentebibel, S.; Moyano, E.; Palazón, J.; Cusidó, R. M.; Eibl-Schindler, Regine; Piñol, M. T.

doi:10.21256/zhaw-1555

Please use this identifier to cite or link to this item: https://doi.org/10.21256/zhaw-1555

Publication type:	Article in scientific journal
Type of review:	Peer review (publication)
Title:	Paclitaxel and baccatin III production induced by methyl jasmonate in free and immobilized cells of Taxus baccata
Authors:	Bonfill, M. Bentebibel, S. Moyano, E. Palazón, J. Cusidó, R. M. Eibl-Schindler, Regine Piñol, M. T.
DOI:	10.21256/zhaw-1555 10.1007/s10535-007-0137-2
Published in:	Biologia Plantarum
Volume(Issue):	51
Issue:	4
Page(s):	647
Pages to:	652
Issue Date:	2007
Publisher / Ed. Institution:	Springer
ISSN:	0006-3134 1573-8264
Language:	English
Subject (DDC):	660.6: Biotechnology
Abstract:	The effects of 100 and 200 µM methyl jasmonate (MJA) on cell proliferation and paclitaxel and baccatin III production were investigated in free and alginate immobilized cells of Taxus baccata growing in a selected product formation culture medium. The greatest accumulation of paclitaxel (13.20 mg dm−3) and baccatin III (4.62 mg dm−3) occurred when 100 µM MJA was added to the culture medium of cells entrapped using a 1.5 and 2.5 % alginate solution. The effects of different treatments on the viability of cultured cells and their capacity to excrete both taxanes into the surrounding medium were considered.
Further description:	Erworben im Rahmen der Schweizer Nationallizenzen (http://www.nationallizenzen.ch)
URI:	https://digitalcollection.zhaw.ch/handle/11475/2095
Fulltext version:	Published version
License (according to publishing contract):	Licence according to publishing contract
Restricted until:	2013-01-01
Departement:	Life Sciences and Facility Management
Appears in collections:	Publikationen Life Sciences und Facility Management

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Bonfill, M., Bentebibel, S., Moyano, E., Palazón, J., Cusidó, R. M., Eibl-Schindler, R., & Piñol, M. T. (2007). Paclitaxel and baccatin III production induced by methyl jasmonate in free and immobilized cells of Taxus baccata. Biologia Plantarum, 51(4), 647–652. https://doi.org/10.21256/zhaw-1555

Bonfill, M. et al. (2007) ‘Paclitaxel and baccatin III production induced by methyl jasmonate in free and immobilized cells of Taxus baccata’, Biologia Plantarum, 51(4), pp. 647–652. Available at: https://doi.org/10.21256/zhaw-1555.

M. Bonfill et al., “Paclitaxel and baccatin III production induced by methyl jasmonate in free and immobilized cells of Taxus baccata,” Biologia Plantarum, vol. 51, no. 4, pp. 647–652, 2007, doi: 10.21256/zhaw-1555.

BONFILL, M., S. BENTEBIBEL, E. MOYANO, J. PALAZÓN, R. M. CUSIDÓ, Regine EIBL-SCHINDLER und M. T. PIÑOL, 2007. Paclitaxel and baccatin III production induced by methyl jasmonate in free and immobilized cells of Taxus baccata. Biologia Plantarum. 2007. Bd. 51, Nr. 4, S. 647–652. DOI 10.21256/zhaw-1555

Bonfill, M., S. Bentebibel, E. Moyano, J. Palazón, R. M. Cusidó, Regine Eibl-Schindler, and M. T. Piñol. 2007. “Paclitaxel and Baccatin III Production Induced by Methyl Jasmonate in Free and Immobilized Cells of Taxus Baccata.” Biologia Plantarum 51 (4): 647–52. https://doi.org/10.21256/zhaw-1555.

Bonfill, M., et al. “Paclitaxel and Baccatin III Production Induced by Methyl Jasmonate in Free and Immobilized Cells of Taxus Baccata.” Biologia Plantarum, vol. 51, no. 4, 2007, pp. 647–52, https://doi.org/10.21256/zhaw-1555.