Please use this identifier to cite or link to this item: https://doi.org/10.21256/zhaw-20474
Publication type: Article in scientific journal
Type of review: Open peer review
Title: Comparative efficacy of placebos in short-term antidepressant trials for major depression : a secondary meta-analysis of placebo-controlled trials
Authors : Holper, Lisa
Hengartner, Michael Pascal
et. al : No
DOI : 10.1186/s12888-020-02839-y
10.21256/zhaw-20474
Published in : BMC Psychiatry
Volume(Issue) : 20
Issue : 1
Pages : 437
Issue Date: 2020
Publisher / Ed. Institution : BioMed Central
ISSN: 1471-244X
Language : English
Subjects : Antidepressants; Bayesian network meta-analysis; Placebo; Side-effects; Unblinding
Subject (DDC) : 615: Pharmacology and therapeutics
616.8: Neurology, diseases of nervous system
Abstract: The issue of unblinded outcome-assessors and patients has repeatedly been stressed as a flaw in allegedly double-blind antidepressant trials. Unblinding bias can for example result from a drug's marked side effects. If such unblinding bias is present for a given drug, then it might be expected that the placebos of that drug are rated significantly less effective than that of other antidepressants.
URI: https://digitalcollection.zhaw.ch/handle/11475/20474
Fulltext version : Published version
License (according to publishing contract) : Licence according to publishing contract
Departement: Applied Psychology
Organisational Unit: Psychological Institute (PI)
Appears in Collections:Publikationen Angewandte Psychologie

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