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Title: Appetite-suppressing and satiety-increasing bioactive phytochemicals : a systematic review
Authors : Stuby, Johann
Gravestock, Isaac
Wolfram, Evelyn
Pichierri, Giuseppe
Steurer, Johann
Burgstaller, Jakob M.
et. al : No
Published in : Nutrients
Volume(Issue) : 11
Issue : 9
Pages : 2238
Publisher / Ed. Institution : MDPI
Issue Date: 2019
License (according to publishing contract) : CC BY 4.0: Attribution 4.0 International
Type of review: Peer review (publication)
Language : English
Subjects : Appetite; Bioactive phytochemicals; Fullness; Hunger; Plant extracts; Satiety
Subject (DDC) : 572: Biochemistry
Abstract: The prevalence of obesity is increasing worldwide. Bioactive phytochemicals in food supplements are a trending approach to facilitate dieting and to improve patients' adherence to reducing food and caloric intake. The aim of this systematic review was to assess efficacy and safety of the most commonly used bioactive phytochemicals with appetite/hunger-suppressing and/or satiety/fullness-increasing properties. To be eligible, studies needed to have included at least 10 patients per group aged 18 years or older with no serious health problems except for overweight or obesity. Of those studies, 32 met the inclusion criteria, in which 27 different plants were tested alone or as a combination, regarding their efficacy in suppressing appetite/hunger and/or increasing satiety/fullness. The plant extracts most tested were derived from Camellia sinensis (green tea), Capsicum annuum, and Coffea species. None of the plant extracts tested in several trials showed a consistent positive treatment effect. Furthermore, only a few adverse events were reported, but none serious. The findings revealed mostly inconclusive evidence that the tested bioactive phytochemicals are effective in suppressing appetite/hunger and/or increasing satiety/fullness. More systematic and high quality clinical studies are necessary to determine the benefits and safety of phytochemical complementary remedies for dampening the feeling of hunger during dieting.
Departement: Life Sciences and Facility Management
Organisational Unit: Institute of Chemistry and Biotechnology (ICBT)
Publication type: Article in scientific journal
DOI : 10.3390/nu11092238
ISSN: 2072-6643
Appears in Collections:Publikationen Life Sciences und Facility Management

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