Please use this identifier to cite or link to this item:
https://doi.org/10.21256/zhaw-1520Full metadata record
| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | Ishimaru, Carol | - |
| dc.contributor.author | Lansdell, Teresa A. | - |
| dc.contributor.author | Clardy, Jon | - |
| dc.contributor.author | Duffy, Brion | - |
| dc.contributor.author | Smits, Theo H.M. | - |
| dc.date.accessioned | 2017-12-08T09:58:59Z | - |
| dc.date.available | 2017-12-08T09:58:59Z | - |
| dc.date.issued | 2017-11 | - |
| dc.identifier.issn | 2239-7264 | de_CH |
| dc.identifier.uri | https://digitalcollection.zhaw.ch/handle/11475/1741 | - |
| dc.description.abstract | Pantoea vagans C9-1 is one of the most effective and reliable biocontrol agents against fire blight, and has been commercialized as Blight Ban C9-1. Production of multiple antibiotics contributes to its antagonism of Erwinia amylovora. Here we describe the genetics, chemical isolation and structure of herbicolin O, the histidine-reversible antibiotic produced by P. vagans C9-1. Mutational analyses indicated that biosynthesis of herbicolin O depends on paaAB and a sequence encoding the peptide precursor of pantocin A. The paaABC gene cluster encoding biosynthesis and autoresistance was located within a 28-kb chromosomal genomic island of the complete genome sequence of P. vagans C9-1. The cluster was cloned and expressed in E. coli and purified antibiotic was isolated using improved methods for small peptides. The 1H NMR spectra of the C9-1 antibiotic closely resembled those of pantocin A produced by P. agglomerans Eh318. Detailed analysis of the proton spin systems showed that the chemical shift values and coupling constants of the protons in C9-1 herbicolin O correspond exactly to those of pantocin A. Based on these genetic and chemical analyses, herbicolin O and pantocin A are confirmed to be the same antibiotic. | de_CH |
| dc.language.iso | en | de_CH |
| dc.publisher | Edizioni ETS | de_CH |
| dc.relation.ispartof | Journal of Plant Pathology | de_CH |
| dc.rights | Licence according to publishing contract | de_CH |
| dc.subject | Fire blight | de_CH |
| dc.subject | Biocontrol | de_CH |
| dc.subject | Herbicolin O | de_CH |
| dc.subject | Peptide antibiotic | de_CH |
| dc.subject.ddc | 570: Biologie | de_CH |
| dc.subject.ddc | 630: Landwirtschaft | de_CH |
| dc.title | The histidine-reversible antibiotic herbicolin O produced by Pantoea vagans C9-1 is pantocin A | de_CH |
| dc.type | Beitrag in wissenschaftlicher Zeitschrift | de_CH |
| dcterms.type | Text | de_CH |
| zhaw.departement | Life Sciences und Facility Management | de_CH |
| zhaw.organisationalunit | Institut für Umwelt und Natürliche Ressourcen (IUNR) | de_CH |
| dc.identifier.doi | 10.4454/jpp.v99i0.3910 | de_CH |
| dc.identifier.doi | 10.21256/zhaw-1520 | - |
| zhaw.funding.eu | No | de_CH |
| zhaw.issue | Special issue | de_CH |
| zhaw.originated.zhaw | Yes | de_CH |
| zhaw.pages.end | 97 | de_CH |
| zhaw.pages.start | 91 | de_CH |
| zhaw.publication.status | publishedVersion | de_CH |
| zhaw.volume | 99 | de_CH |
| zhaw.publication.review | Peer review (Publikation) | de_CH |
| zhaw.webfeed | Umweltgenomik | de_CH |
| zhaw.funding.zhaw | Genomik und Transkriptomik von Erwinia und Pantoea | de_CH |
| Appears in collections: | Publikationen Life Sciences und Facility Management | |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| 57_Ishimaru_JPlantPathol2017.pdf | 315.8 kB | Adobe PDF |  View/Open |
Show simple item record
Ishimaru, C., Lansdell, T. A., Clardy, J., Duffy, B., & Smits, T. H. M. (2017). The histidine-reversible antibiotic herbicolin O produced by Pantoea vagans C9-1 is pantocin A. Journal of Plant Pathology, 99(Special issue), 91–97. https://doi.org/10.4454/jpp.v99i0.3910
Ishimaru, C. et al. (2017) ‘The histidine-reversible antibiotic herbicolin O produced by Pantoea vagans C9-1 is pantocin A’, Journal of Plant Pathology, 99(Special issue), pp. 91–97. Available at: https://doi.org/10.4454/jpp.v99i0.3910.
C. Ishimaru, T. A. Lansdell, J. Clardy, B. Duffy, and T. H. M. Smits, “The histidine-reversible antibiotic herbicolin O produced by Pantoea vagans C9-1 is pantocin A,” Journal of Plant Pathology, vol. 99, no. Special issue, pp. 91–97, Nov. 2017, doi: 10.4454/jpp.v99i0.3910.
ISHIMARU, Carol, Teresa A. LANSDELL, Jon CLARDY, Brion DUFFY und Theo H.M. SMITS, 2017. The histidine-reversible antibiotic herbicolin O produced by Pantoea vagans C9-1 is pantocin A. Journal of Plant Pathology. November 2017. Bd. 99, Nr. Special issue, S. 91–97. DOI 10.4454/jpp.v99i0.3910
Ishimaru, Carol, Teresa A. Lansdell, Jon Clardy, Brion Duffy, and Theo H.M. Smits. 2017. “The Histidine-Reversible Antibiotic Herbicolin O Produced by Pantoea Vagans C9-1 Is Pantocin A.” Journal of Plant Pathology 99 (Special issue): 91–97. https://doi.org/10.4454/jpp.v99i0.3910.
Ishimaru, Carol, et al. “The Histidine-Reversible Antibiotic Herbicolin O Produced by Pantoea Vagans C9-1 Is Pantocin A.” Journal of Plant Pathology, vol. 99, no. Special issue, Nov. 2017, pp. 91–97, https://doi.org/10.4454/jpp.v99i0.3910.
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.