| Publikationstyp: | Beitrag in wissenschaftlicher Zeitschrift |
| Art der Begutachtung: | Peer review (Publikation) |
| Titel: | Synthetic 3D multicellular systems for drug development |
| Autor/-in: | Rimann, Markus Graf-Hausner, Ursula |
| DOI: | 10.1016/j.copbio.2012.01.011 |
| Erschienen in: | Current Opinion in Biotechnology |
| Band(Heft): | 23 |
| Heft: | 5 |
| Seite(n): | 803 |
| Seiten bis: | 809 |
| Erscheinungsdatum: | 2012 |
| Verlag / Hrsg. Institution: | Elsevier |
| ISSN: | 0958-1669 1879-0429 |
| Sprache: | Englisch |
| Fachgebiet (DDC): | 615: Pharmakologie und Therapeutik 660.6: Biotechnologie |
| Zusammenfassung: | Since the 1970s, the limitations of two dimensional (2D) cell culture and the relevance of appropriate three dimensional (3D) cell systems have become increasingly evident. Extensive effort has thus been made to move cells from a flat world to a 3D environment. While 3D cell culture technologies are meanwhile widely used in academia, 2D culture technologies are still entrenched in the (pharmaceutical) industry for most kind of cell-based efficacy and toxicology tests. However, 3D cell culture technologies will certainly become more applicable if biological relevance, reproducibility and high throughput can be assured at acceptable costs. Most recent innovations and developments clearly indicate that the transition from 2D to 3D cell culture for industrial purposes, for example, drug development is simply a question of time. |
| URI: | https://digitalcollection.zhaw.ch/handle/11475/1604 |
| Volltext Version: | Publizierte Version |
| Lizenz (gemäss Verlagsvertrag): | Lizenz gemäss Verlagsvertrag |
| Departement: | Life Sciences und Facility Management |
| Enthalten in den Sammlungen: | Publikationen Life Sciences und Facility Management |
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Zur Langanzeige
Rimann, M., & Graf-Hausner, U. (2012). Synthetic 3D multicellular systems for drug development. Current Opinion in Biotechnology, 23(5), 803–809. https://doi.org/10.1016/j.copbio.2012.01.011
Rimann, M. and Graf-Hausner, U. (2012) ‘Synthetic 3D multicellular systems for drug development’, Current Opinion in Biotechnology, 23(5), pp. 803–809. Available at: https://doi.org/10.1016/j.copbio.2012.01.011.
M. Rimann and U. Graf-Hausner, “Synthetic 3D multicellular systems for drug development,” Current Opinion in Biotechnology, vol. 23, no. 5, pp. 803–809, 2012, doi: 10.1016/j.copbio.2012.01.011.
RIMANN, Markus und Ursula GRAF-HAUSNER, 2012. Synthetic 3D multicellular systems for drug development. Current Opinion in Biotechnology. 2012. Bd. 23, Nr. 5, S. 803–809. DOI 10.1016/j.copbio.2012.01.011
Rimann, Markus, and Ursula Graf-Hausner. 2012. “Synthetic 3D Multicellular Systems for Drug Development.” Current Opinion in Biotechnology 23 (5): 803–9. https://doi.org/10.1016/j.copbio.2012.01.011.
Rimann, Markus, and Ursula Graf-Hausner. “Synthetic 3D Multicellular Systems for Drug Development.” Current Opinion in Biotechnology, vol. 23, no. 5, 2012, pp. 803–9, https://doi.org/10.1016/j.copbio.2012.01.011.
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