|Title:||Prolonged cytotoxic effect of aqueous extracts from dired Viscum album on bladder cancer cells|
|Authors :||Hunziker-Basler, N.|
|Published in :||Die Pharmazie|
|Publisher / Ed. Institution :||Avoxa|
|License (according to publishing contract) :||Licence according to publishing contract|
|Type of review:||Peer review (Publication)|
|Subject (DDC) :||615: Pharmacology and therapeutics|
|Abstract:||Aqueous extracts from whole dried mistletoe (Viscum album L., Iscucin®) are often used in anti-cancer treatment. We studied the effect of extracts obtained from mistletoe bushes that grew on different host trees on bladder cancer cells by means of MTT-colorimetric cell proliferation/survival assays. The extracts possessed concentration-dependent cytotoxic properties whose extent varied with the host tree, but did not always correlate with the corresponding mistletoe lectin content. A 2-hours treatment of bladder cancer cells triggered a later, strong cytotoxic effect. This prolonged effect suggests that instillation with Iscucin® has therapeutic potential for bladder cancer patients.|
|Departement:||Life Sciences and Facility Management|
|Organisational Unit:||Institute of Chemistry and Biotechnology (ICBT)|
|Publication type:||Article in scientific Journal|
|Appears in Collections:||Publikationen Life Sciences und Facility Management|
Files in This Item:
There are no files associated with this item.
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.