|Publication type:||Article in scientific journal|
|Type of review:||Peer review (publication)|
|Title:||Prolonged cytotoxic effect of aqueous extracts from dired Viscum album on bladder cancer cells|
|Published in:||Die Pharmazie|
|Publisher / Ed. Institution:||Avoxa|
|Subject (DDC):||615: Pharmacology and therapeutics|
|Abstract:||Aqueous extracts from whole dried mistletoe (Viscum album L., Iscucin®) are often used in anti-cancer treatment. We studied the effect of extracts obtained from mistletoe bushes that grew on different host trees on bladder cancer cells by means of MTT-colorimetric cell proliferation/survival assays. The extracts possessed concentration-dependent cytotoxic properties whose extent varied with the host tree, but did not always correlate with the corresponding mistletoe lectin content. A 2-hours treatment of bladder cancer cells triggered a later, strong cytotoxic effect. This prolonged effect suggests that instillation with Iscucin® has therapeutic potential for bladder cancer patients.|
|Fulltext version:||Published version|
|License (according to publishing contract):||Licence according to publishing contract|
|Departement:||Life Sciences and Facility Management|
|Organisational Unit:||Institute of Chemistry and Biotechnology (ICBT)|
|Appears in Collections:||Publikationen Life Sciences und Facility Management|
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