Issue Date | Title | Involved Person(s) |
30-Dec-2019 | CyBy2 : a strongly typed, purely functional framework for chemical data management | Höck, Stefan; Riedl, Rainer |
10-Jun-2019 | Approaching target selectivity by de novo drug design | Fischer, Thomas; Gazzola, Silvia; Riedl, Rainer |
1-May-2019 | Durch die Natur inspiriertes Wirkstoffdesign | Gall, Flavio; Riedl, Rainer; Sievers, Martin; Wermelinger, Tobias; Frasson, David |
18-Feb-2019 | Cover picture : drug design inspired by nature : crystallographic detection of an auto‐tailored protease inhibitor template (Angew. Chem. Int. Ed. 12/2019) | Gall, Flavio; Hohl, Deborah; Frasson, David; Wermelinger, Tobias; Mittl, Peer R. E., et al |
18-Feb-2019 | Titelbild: Von der Natur inspiriertes Wirkstoffdesign : kristallographische Detektion eines selbstgenerierten Inhibitor‐Grundgerüsts (Angew. Chem. 12/2019) | Gall, Flavio M.; Hohl, Deborah; Frasson, David; Wermelinger, Tobias; Mittl, Peer R. E., et al |
5-Feb-2019 | Design and structural evolution of matrix metalloproteinase inhibitors | Fischer, Thomas; Senn, Nicole; Riedl, Rainer |
7-Jan-2019 | Drug design inspired by nature : crystallographic detection of an auto‐tailored protease inhibitor template | Gall, Flavio; Hohl, Deborah; Frasson, David; Wermelinger, Tobias; Mittl, Peer R. E., et al |
7-Jan-2019 | Von der Natur inspiriertes Wirkstoffdesign : kristallographische Detektion eines selbstgenerierten Inhibitor‐Grundgerüsts | Gall, Flavio; Hohl, Deborah; Frasson, David; Wermelinger, Tobias; Mittl, Peer R. E., et al |
2019 | High consistency of structure-based design and x-ray crystallography : design, synthesis, kinetic evaluation and crystallographic binding mode determination of biphenyl-N-acyl-β-D-glucopyranosylamines as glycogen phosphorylase inhibitors | Fischer, Thomas; Koulas, Symeon M.; Tsagkarakou, Anastasia S.; Kyriakis, Efthimios; Stravodimos, George A., et al |
2019 | Inhibitory antibodies designed for matrix metalloproteinase modulation | Fischer, Thomas; Riedl, Rainer |
5-Oct-2018 | Primary resistance mechanism of the canine distemper virus fusion protein against a small-molecule membrane fusion inhibitor | Kalbermatter, David; Shrestha, Neeta; Ader-Ebert, Nadine; Herren, Michael; Moll, Pascal, et al |
30-May-2018 | A Structural view on medicinal chemistry strategies against drug resistance | Agnello, Stefano; Brand, Michael; Chellat, Mathieu; Gazzola, Silvia; Riedl, Rainer |
30-May-2018 | Eine strukturelle Evaluierung medizinalchemischer Strategien gegen Wirkstoffresistenzen | Agnello, Stefano; Brand, Michael; Chellat, Mathieu; Gazzola, Silvia; Riedl, Rainer |
2017 | Targeted polypharmacology : discovery of a highly potent non-hydroxamate dual matrix metalloproteinase (MMP)-10/-13 inhibitor | Senn, Nicole; Ott, Michael; Lanz, Jan; Riedl, Rainer |
2017 | Targeted fluoro positioning for the discovery of a potent and highly selective matrix metalloproteinase inhibitor | Fischer, Thomas; Riedl, Rainer |