Please use this identifier to cite or link to this item:
https://doi.org/10.21256/zhaw-3882
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DC Field | Value | Language |
---|---|---|
dc.contributor.author | Zoller, Stefan | - |
dc.contributor.author | Boskova, Veronika | - |
dc.contributor.author | Anisimova, Maria | - |
dc.date.accessioned | 2018-07-17T14:49:28Z | - |
dc.date.available | 2018-07-17T14:49:28Z | - |
dc.date.issued | 2015 | - |
dc.identifier.issn | 0737-4038 | de_CH |
dc.identifier.issn | 1537-1719 | de_CH |
dc.identifier.uri | https://digitalcollection.zhaw.ch/handle/11475/8260 | - |
dc.description | Erworben im Rahmen der Schweizer Nationallizenzen (http://www.nationallizenzen.ch) | de_CH |
dc.description.abstract | Many protein sequences have distinct domains that evolve with different rates, different selective pressures, or may differ in codon bias. Instead of modeling these differences by more and more complex models of molecular evolution, we present a multipartition approach that allows maximum-likelihood phylogeny inference using different codon models at predefined partitions in the data. Partition models can, but do not have to, share free parameters in the estimation process. We test this approach with simulated data as well as in a phylogenetic study of the origin of the leucin-rich repeat regions in the type III effector proteins of the pythopathogenic bacteria Ralstonia solanacearum. Our study does not only show that a simple two-partition model resolves the phylogeny better than a one-partition model but also gives more evidence supporting the hypothesis of lateral gene transfer events between the bacterial pathogens and its eukaryotic hosts. | de_CH |
dc.language.iso | en | de_CH |
dc.publisher | Oxford University Press | de_CH |
dc.relation.ispartof | Molecular Biology and Evolution | de_CH |
dc.rights | Licence according to publishing contract | de_CH |
dc.subject | Markov model | de_CH |
dc.subject | Amino acid substitution model | de_CH |
dc.subject | Codon substitution model | de_CH |
dc.subject | Maximum-likelihood tree | de_CH |
dc.subject | Bacterial protein | de_CH |
dc.subject | Ralstonia solanacearum | de_CH |
dc.subject | Codon | de_CH |
dc.subject | Genetic model | de_CH |
dc.subject.ddc | 572: Biochemie | de_CH |
dc.title | Maximum-likelihood tree estimation using codon substitution models with multiple partitions | de_CH |
dc.type | Beitrag in wissenschaftlicher Zeitschrift | de_CH |
dcterms.type | Text | de_CH |
zhaw.departement | Life Sciences und Facility Management | de_CH |
zhaw.organisationalunit | Institut für Computational Life Sciences (ICLS) | de_CH |
dc.identifier.doi | 10.21256/zhaw-3882 | - |
dc.identifier.doi | 10.1093/molbev/msv097 | de_CH |
dc.identifier.pmid | 25911229 | de_CH |
zhaw.funding.eu | No | de_CH |
zhaw.issue | 8 | de_CH |
zhaw.originated.zhaw | Yes | de_CH |
zhaw.pages.end | 2216 | de_CH |
zhaw.pages.start | 2208 | de_CH |
zhaw.publication.status | publishedVersion | de_CH |
zhaw.volume | 32 | de_CH |
zhaw.embargo.end | 2019-01-01 | de_CH |
zhaw.publication.review | Peer review (Publikation) | de_CH |
zhaw.webfeed | Computational Genomics | de_CH |
Appears in collections: | Publikationen Life Sciences und Facility Management |
Files in This Item:
File | Description | Size | Format | |
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msv097.pdf | 788.77 kB | Adobe PDF | View/Open |
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Zoller, S., Boskova, V., & Anisimova, M. (2015). Maximum-likelihood tree estimation using codon substitution models with multiple partitions. Molecular Biology and Evolution, 32(8), 2208–2216. https://doi.org/10.21256/zhaw-3882
Zoller, S., Boskova, V. and Anisimova, M. (2015) ‘Maximum-likelihood tree estimation using codon substitution models with multiple partitions’, Molecular Biology and Evolution, 32(8), pp. 2208–2216. Available at: https://doi.org/10.21256/zhaw-3882.
S. Zoller, V. Boskova, and M. Anisimova, “Maximum-likelihood tree estimation using codon substitution models with multiple partitions,” Molecular Biology and Evolution, vol. 32, no. 8, pp. 2208–2216, 2015, doi: 10.21256/zhaw-3882.
ZOLLER, Stefan, Veronika BOSKOVA und Maria ANISIMOVA, 2015. Maximum-likelihood tree estimation using codon substitution models with multiple partitions. Molecular Biology and Evolution. 2015. Bd. 32, Nr. 8, S. 2208–2216. DOI 10.21256/zhaw-3882
Zoller, Stefan, Veronika Boskova, and Maria Anisimova. 2015. “Maximum-Likelihood Tree Estimation Using Codon Substitution Models with Multiple Partitions.” Molecular Biology and Evolution 32 (8): 2208–16. https://doi.org/10.21256/zhaw-3882.
Zoller, Stefan, et al. “Maximum-Likelihood Tree Estimation Using Codon Substitution Models with Multiple Partitions.” Molecular Biology and Evolution, vol. 32, no. 8, 2015, pp. 2208–16, https://doi.org/10.21256/zhaw-3882.
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