Please use this identifier to cite or link to this item: https://doi.org/10.21256/zhaw-3558
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dc.contributor.authorScheidegger, Stephan-
dc.contributor.authorFüchslin, Rudolf Marcel-
dc.date.accessioned2018-03-21T12:28:13Z-
dc.date.available2018-03-21T12:28:13Z-
dc.date.issued2011-
dc.identifier.isbn978-3-905745-44-3de_CH
dc.identifier.urihttps://digitalcollection.zhaw.ch/handle/11475/4141-
dc.description.abstractThe response of tumours onto ionizing radiation cannot be fully understood by commonly used radiobiological models. The reason may lie in the complex structure of the cellular systems which show a high degree of compartmentalisation and which is characterised by a network of interacting processes at different time scales. To access the dynamic response of cells onto radiation, compartmental models based on a biological dose equivalent can be used. Two different models (T-LQ- and T-IR-model) are used to fit experimental data of the clonogenic survival of irradiated cells at very high dose rates. The models reveal the correct dose rate dependence over a wide range of the parameter space when adapting the kinetic constants to the dose rate. This adaption could be an indication for the multi-scale structure of the system.de_CH
dc.language.isoende_CH
dc.publisherArbeitsgemeinschaft Simulationde_CH
dc.rightsLicence according to publishing contractde_CH
dc.subjectRadiationde_CH
dc.subjectRadiobiologyde_CH
dc.subjectEmergencede_CH
dc.subjectDose equivalentde_CH
dc.subject.ddc615: Pharmakologie und Therapeutikde_CH
dc.titleKinetic model for dose equivalent : an efficient way to predict systems response of irradiated cellsde_CH
dc.typeKonferenz: Paperde_CH
dcterms.typeTextde_CH
zhaw.departementSchool of Engineeringde_CH
dc.identifier.doi10.21256/zhaw-3558-
zhaw.conference.details21. Symposium Simulationstechnik (ASIM 2011), Winterthur, 7-9 September 2011de_CH
zhaw.funding.euNode_CH
zhaw.originated.zhawYesde_CH
zhaw.parentwork.editorBödi, Richard-
zhaw.parentwork.editorMaurer, Werner-
zhaw.publication.statuspublishedVersionde_CH
zhaw.publication.reviewPeer review (Abstract)de_CH
zhaw.title.proceedingsProceedings of ASIM 2011 : Grundlagen, Methoden und Anwendungen in Modellbildung und Simulationde_CH
Appears in collections:Publikationen School of Engineering

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Scheidegger, S., & Füchslin, R. M. (2011). Kinetic model for dose equivalent : an efficient way to predict systems response of irradiated cells [Conference paper]. In R. Bödi & W. Maurer (Eds.), Proceedings of ASIM 2011 : Grundlagen, Methoden und Anwendungen in Modellbildung und Simulation. Arbeitsgemeinschaft Simulation. https://doi.org/10.21256/zhaw-3558
Scheidegger, S. and Füchslin, R.M. (2011) ‘Kinetic model for dose equivalent : an efficient way to predict systems response of irradiated cells’, in R. Bödi and W. Maurer (eds) Proceedings of ASIM 2011 : Grundlagen, Methoden und Anwendungen in Modellbildung und Simulation. Arbeitsgemeinschaft Simulation. Available at: https://doi.org/10.21256/zhaw-3558.
S. Scheidegger and R. M. Füchslin, “Kinetic model for dose equivalent : an efficient way to predict systems response of irradiated cells,” in Proceedings of ASIM 2011 : Grundlagen, Methoden und Anwendungen in Modellbildung und Simulation, 2011. doi: 10.21256/zhaw-3558.
SCHEIDEGGER, Stephan und Rudolf Marcel FÜCHSLIN, 2011. Kinetic model for dose equivalent : an efficient way to predict systems response of irradiated cells. In: Richard BÖDI und Werner MAURER (Hrsg.), Proceedings of ASIM 2011 : Grundlagen, Methoden und Anwendungen in Modellbildung und Simulation. Conference paper. Arbeitsgemeinschaft Simulation. 2011. ISBN 978-3-905745-44-3
Scheidegger, Stephan, and Rudolf Marcel Füchslin. 2011. “Kinetic Model for Dose Equivalent : An Efficient Way to Predict Systems Response of Irradiated Cells.” Conference paper. In Proceedings of ASIM 2011 : Grundlagen, Methoden Und Anwendungen in Modellbildung Und Simulation, edited by Richard Bödi and Werner Maurer. Arbeitsgemeinschaft Simulation. https://doi.org/10.21256/zhaw-3558.
Scheidegger, Stephan, and Rudolf Marcel Füchslin. “Kinetic Model for Dose Equivalent : An Efficient Way to Predict Systems Response of Irradiated Cells.” Proceedings of ASIM 2011 : Grundlagen, Methoden Und Anwendungen in Modellbildung Und Simulation, edited by Richard Bödi and Werner Maurer, Arbeitsgemeinschaft Simulation, 2011, https://doi.org/10.21256/zhaw-3558.


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