Issue Date | Title | Involved Person(s) |
2017 | Emodin : a compound with putative antidiabetic potential, deteriorates glucose tolerance in rodents | Abu Eid, Sameer; Adams, Michael; Scherer, Thomas; Torres-Gómez, Héctor Manuel; Hackl, Martina Theresa; Kaplanian, Mairam; Riedl, Rainer; Luger, Anton; Fürnsinn, Clemens |
2017 | Cover profile : targeted fluoro positioning for the discovery of a potent and highly selective matrix metalloproteinase inhibitor | Fischer, Thomas; Riedl, Rainer |
2017 | Cover picture : targeted fluoro positioning for the discovery of a potent and highly selective matrix metalloproteinase inhibitor (ChemistryOpen 2/2017) | Fischer, Thomas; Riedl, Rainer |
2017 | Targeted polypharmacology : discovery of a highly potent non-hydroxamate dual matrix metalloproteinase (MMP)-10/-13 inhibitor | Senn, Nicole; Ott, Michael; Lanz, Jan; Riedl, Rainer |
2017 | Targeted fluoro positioning for the discovery of a potent and highly selective matrix metalloproteinase inhibitor | Fischer, Thomas; Riedl, Rainer |
2016 | Molecular recognition of the catalytic zinc(II) ion in MMP-13 : structure-based evolution of an allosteric inhibitor to dual binding mode inhibitors with improved lipophilic ligand efficiencies | Fischer, Thomas; Riedl, Rainer |
2015 | Merging allosteric and active site binding motifs : de novo generation of target selectivity and potency via natural-product-derived fragments | Lanz, Jan; Riedl, Rainer |
2015 | Highly oxygenated sesquiterpenes in Artemisia alba Turra | Todorova, Milka; Trendafilova, Antoaneta; Danova, Kalina; Simmons, Luke; Wolfram, Evelyn; Meier, Beat; Riedl, Rainer; Evstatieva, Luba |
2014 | Nicht nur Metalloproteasen im Visier | Riedl, Rainer |
Jan-2013 | Drug discovery through a chemist’s eyes | Riedl, Rainer |
2013 | Strategic targeting of multiple water-mediated interactions : a concise and rational structure-based design approach to potent and selective MMP-13 inhibitors | Fischer, Thomas; Riedl, Rainer |
2012 | Structure based design and synthesis of novel MMP inhibitors | Riedl, Rainer; Fischer, Thomas |
2012 | Design, synthesis and biological testing of novel MMP-inhibitors | Fischer, Thomas; Riedl, Rainer |
2012 | Synthese und medizinalchemische Optimierung von Tetrazyklinanaloga | Riedl, Rainer; Brand, Michael |
Sep-2011 | Structure based design and synthesis of novel MMP inhibitors | Riedl, Rainer; Fischer, Thomas; Züger, Patrik; Brand, Michael |