Pre-schoolers suffering from psychiatric disorders show increased cortisol secretion and poor sleep compared to healthy controls

Hatzinger, Martin; Brand, Serge; Perren, Sonja; von Wyl, Agnes; Stadelmann, Stephanie; von Klitzing, Kai; Holsboer-Trachsler, Edith

doi:10.1016/j.jpsychires.2012.01.018

Publication type:	Article in scientific journal
Type of review:	Peer review (publication)
Title:	Pre-schoolers suffering from psychiatric disorders show increased cortisol secretion and poor sleep compared to healthy controls
Authors:	Hatzinger, Martin Brand, Serge Perren, Sonja von Wyl, Agnes Stadelmann, Stephanie von Klitzing, Kai Holsboer-Trachsler, Edith
DOI:	10.1016/j.jpsychires.2012.01.018
Published in:	Journal of Psychiatric Research
Volume(Issue):	46
Issue:	5
Page(s):	590
Pages to:	599
Issue Date:	May-2012
Publisher / Ed. Institution:	Elsevier
ISSN:	0022-3956 1879-1379
Language:	English
Subjects:	Cortisol; Sleep; Actigraphy; Pre-schooler; Psychiatric disorder
Subject (DDC):	610: Medicine and health 616.89: Mental disorders, clinical psychology and psychiatry
Abstract:	Background: Various studies of child cortisol secretion and sleep show a close association between poor sleep, deterioration of the HPA axis and unfavorable psychological functioning. However, there is little evidence as to whether these associations are clearly present in pre-school children suffering from psychiatric disorders. Method: A total of 30 pre-schoolers suffering from psychiatric disorders (anxiety, adjustment disorders, emotional and attachment disorder; hyperactivity or oppositional disorder) and 35 healthy controls took part in the study. Saliva cortisol secretion was assessed both at baseline and under challenge conditions. Sleep was assessed via activity monitoring for seven consecutive days and nights, using a digital movement-measuring instrument. Parents and teachers completed questionnaires assessing children's cognitive, emotional and social functioning. The Berkeley Puppet Interview provided child-based reports of cognitive–emotional processes. Results: Compared to healthy controls, children suffering from psychiatric disorders had much higher cortisol secretion both at baseline and under challenge conditions. Sleep was also more disturbed, and parents and teachers rated children suffering from psychiatric disorders as cognitively, emotionally and behaviorally more impaired, relative to healthy controls. Children with psychiatric disorders reported being more bullied and victimized. Conclusions: In five-year old children the presence of psychiatric disorders is reflected not only at psychological, social and behavioral, but also at neuroendocrine and sleep-related levels. It is likely that these children remain at increased risk for suffering from psychiatric difficulties later in life.
URI:	https://digitalcollection.zhaw.ch/handle/11475/3469
Fulltext version:	Published version
License (according to publishing contract):	Licence according to publishing contract
Departement:	Applied Psychology
Organisational Unit:	Psychological Institute (PI)
Appears in collections:	Publikationen Angewandte Psychologie

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Hatzinger, M., Brand, S., Perren, S., von Wyl, A., Stadelmann, S., von Klitzing, K., & Holsboer-Trachsler, E. (2012). Pre-schoolers suffering from psychiatric disorders show increased cortisol secretion and poor sleep compared to healthy controls. Journal of Psychiatric Research, 46(5), 590–599. https://doi.org/10.1016/j.jpsychires.2012.01.018

Hatzinger, M. et al. (2012) ‘Pre-schoolers suffering from psychiatric disorders show increased cortisol secretion and poor sleep compared to healthy controls’, Journal of Psychiatric Research, 46(5), pp. 590–599. Available at: https://doi.org/10.1016/j.jpsychires.2012.01.018.

M. Hatzinger et al., “Pre-schoolers suffering from psychiatric disorders show increased cortisol secretion and poor sleep compared to healthy controls,” Journal of Psychiatric Research, vol. 46, no. 5, pp. 590–599, May 2012, doi: 10.1016/j.jpsychires.2012.01.018.

HATZINGER, Martin, Serge BRAND, Sonja PERREN, Agnes VON WYL, Stephanie STADELMANN, Kai VON KLITZING und Edith HOLSBOER-TRACHSLER, 2012. Pre-schoolers suffering from psychiatric disorders show increased cortisol secretion and poor sleep compared to healthy controls. Journal of Psychiatric Research. Mai 2012. Bd. 46, Nr. 5, S. 590–599. DOI 10.1016/j.jpsychires.2012.01.018

Hatzinger, Martin, Serge Brand, Sonja Perren, Agnes von Wyl, Stephanie Stadelmann, Kai von Klitzing, and Edith Holsboer-Trachsler. 2012. “Pre-Schoolers Suffering from Psychiatric Disorders Show Increased Cortisol Secretion and Poor Sleep Compared to Healthy Controls.” Journal of Psychiatric Research 46 (5): 590–99. https://doi.org/10.1016/j.jpsychires.2012.01.018.

Hatzinger, Martin, et al. “Pre-Schoolers Suffering from Psychiatric Disorders Show Increased Cortisol Secretion and Poor Sleep Compared to Healthy Controls.” Journal of Psychiatric Research, vol. 46, no. 5, May 2012, pp. 590–99, https://doi.org/10.1016/j.jpsychires.2012.01.018.