Cost-effectiveness of physical activity interventions in cancer survivors of developed countries : a systematic review

Gubler-Gut, Barbara E.; Pöhlmann, Johannes; Flatz, Aline; Schwenkglenks, Matthias; Rohrmann, Sabine

doi:10.1007/s11764-021-01002-0

Please use this identifier to cite or link to this item: https://doi.org/10.21256/zhaw-28402

Publication type:	Article in scientific journal
Type of review:	Peer review (publication)
Title:	Cost-effectiveness of physical activity interventions in cancer survivors of developed countries : a systematic review
Authors:	Gubler-Gut, Barbara E. Pöhlmann, Johannes Flatz, Aline Schwenkglenks, Matthias Rohrmann, Sabine
et. al:	No
DOI:	10.1007/s11764-021-01002-0 10.21256/zhaw-28402
Published in:	Journal of Cancer Survivorship
Volume(Issue):	15
Page(s):	961
Pages to:	975
Issue Date:	23-Feb-2021
Publisher / Ed. Institution:	Springer
ISSN:	1932-2259 1932-2267
Language:	English
Subjects:	Cancer survivor; Cost-effectiveness; Cost-utility; Physical activity; Cost-Benefit Analysis; Exercise; Quality of Life; Breast Neoplasms; Cancer Survivors
Subject (DDC):	362.1041: Health economics 616: Internal medicine and diseases
Abstract:	Purpose: Physical activity has been shown to improve survival and quality of life of cancer patients. Due to differences in patient populations, healthcare settings, and types of intervention, cost-effectiveness analyses of physical activity interventions in cancer survivors are difficult to compare. Available evidence from breast cancer survivor research has shown inconsistent results, and transfer of results to other types of cancer is not straightforward. This paper systematically reviewed current evidence on the cost-effectiveness of physical activity interventions in cancer survivors independent of cancer type compared to usual care or another experimental intervention. Methods: The literature search was conducted in seven databases and enhanced by a search for gray literature. Eligible studies were restricted to developed countries and assessed using the CHEERS, CHEC, and PHILIPS checklists. The study protocol was pre-published in PROSPERO. Results: Seven studies, five cost-utility, and two combined cost-utility/cost-effectiveness analyses fully met the inclusion criteria. They covered eight different types of cancer and various interventions. The cost-effectiveness analyses were of moderate to high methodological quality. A high probability of cost-effectiveness was reported in two analyses. One intervention appeared to be not cost-effective, and one to be cost-effective only from an organizational perspective. Three other analyses reported a cost-effectiveness better than US$ 101,195 (€ 80,000) per QALY gained. Conclusions: Physical activity interventions in cancer survivors of developed countries were cost-effective in some but not all clinical trials reviewed. Implications for Cancer Survivors: Cost-effectiveness of physical activity interventions appear to depend upon the intensity of the activity.
URI:	https://digitalcollection.zhaw.ch/handle/11475/28402
Fulltext version:	Published version
License (according to publishing contract):	CC BY 4.0: Attribution 4.0 International
Departement:	School of Health Sciences
Organisational Unit:	Institute of Physiotherapy (IPT) Winterthur Institute of Health Economics (WIG)
Appears in collections:	Publikationen Gesundheit

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Gubler-Gut, B. E., Pöhlmann, J., Flatz, A., Schwenkglenks, M., & Rohrmann, S. (2021). Cost-effectiveness of physical activity interventions in cancer survivors of developed countries : a systematic review. Journal of Cancer Survivorship, 15, 961–975. https://doi.org/10.1007/s11764-021-01002-0

Gubler-Gut, B.E. et al. (2021) ‘Cost-effectiveness of physical activity interventions in cancer survivors of developed countries : a systematic review’, Journal of Cancer Survivorship, 15, pp. 961–975. Available at: https://doi.org/10.1007/s11764-021-01002-0.

B. E. Gubler-Gut, J. Pöhlmann, A. Flatz, M. Schwenkglenks, and S. Rohrmann, “Cost-effectiveness of physical activity interventions in cancer survivors of developed countries : a systematic review,” Journal of Cancer Survivorship, vol. 15, pp. 961–975, Feb. 2021, doi: 10.1007/s11764-021-01002-0.

GUBLER-GUT, Barbara E., Johannes PÖHLMANN, Aline FLATZ, Matthias SCHWENKGLENKS und Sabine ROHRMANN, 2021. Cost-effectiveness of physical activity interventions in cancer survivors of developed countries : a systematic review. Journal of Cancer Survivorship. 23 Februar 2021. Bd. 15, S. 961–975. DOI 10.1007/s11764-021-01002-0

Gubler-Gut, Barbara E., Johannes Pöhlmann, Aline Flatz, Matthias Schwenkglenks, and Sabine Rohrmann. 2021. “Cost-Effectiveness of Physical Activity Interventions in Cancer Survivors of Developed Countries : A Systematic Review.” Journal of Cancer Survivorship 15 (February): 961–75. https://doi.org/10.1007/s11764-021-01002-0.

Gubler-Gut, Barbara E., et al. “Cost-Effectiveness of Physical Activity Interventions in Cancer Survivors of Developed Countries : A Systematic Review.” Journal of Cancer Survivorship, vol. 15, Feb. 2021, pp. 961–75, https://doi.org/10.1007/s11764-021-01002-0.