Synthesis of novel cyclopropylic sulfones and sulfonamides acting as glucokinase activators

Heuser, Stefan; Barrett, David G.; Berg, Martina; Bonnier, Benjamin; Kahl, Astrid; Luz De La Puente, Maria; Oram, Niall; Riedl, Rainer; Roettig, Ulrike; Gil, Gema Sanz; Seger, Erich; Steggles, David J.; Wanner, Jutta; Weichert, Andreas G.

doi:10.1016/j.tetlet.2006.02.110

Publication type:	Article in scientific journal
Type of review:	Peer review (publication)
Title:	Synthesis of novel cyclopropylic sulfones and sulfonamides acting as glucokinase activators
Authors:	Heuser, Stefan Barrett, David G. Berg, Martina Bonnier, Benjamin Kahl, Astrid Luz De La Puente, Maria Oram, Niall Riedl, Rainer Roettig, Ulrike Gil, Gema Sanz Seger, Erich Steggles, David J. Wanner, Jutta Weichert, Andreas G.
DOI:	10.1016/j.tetlet.2006.02.110
Published in:	Tetrahedron Letters
Volume(Issue):	47
Issue:	16
Page(s):	2675
Pages to:	2678
Issue Date:	2006
Publisher / Ed. Institution:	Elsevier
ISSN:	0040-4039 1873-3581
Language:	English
Subjects:	Organic synthesis; Medicinal chemistry; Glucokinase activator
Subject (DDC):	540: Chemistry
Abstract:	A synthetic route towards cyclopropylic compounds, which act as glucokinase activators is described herein. The present synthesis gives easy and rapid access to a wide variety of either sulfones or sulfonamides starting from readily available late-stage intermediates.
URI:	https://digitalcollection.zhaw.ch/handle/11475/2758
Fulltext version:	Published version
License (according to publishing contract):	Licence according to publishing contract
Departement:	Life Sciences and Facility Management
Organisational Unit:	Institute of Chemistry and Biotechnology (ICBT)
Appears in collections:	Publikationen Life Sciences und Facility Management

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Heuser, S., Barrett, D. G., Berg, M., Bonnier, B., Kahl, A., Luz De La Puente, M., Oram, N., Riedl, R., Roettig, U., Gil, G. S., Seger, E., Steggles, D. J., Wanner, J., & Weichert, A. G. (2006). Synthesis of novel cyclopropylic sulfones and sulfonamides acting as glucokinase activators. Tetrahedron Letters, 47(16), 2675–2678. https://doi.org/10.1016/j.tetlet.2006.02.110

Heuser, S. et al. (2006) ‘Synthesis of novel cyclopropylic sulfones and sulfonamides acting as glucokinase activators’, Tetrahedron Letters, 47(16), pp. 2675–2678. Available at: https://doi.org/10.1016/j.tetlet.2006.02.110.

S. Heuser et al., “Synthesis of novel cyclopropylic sulfones and sulfonamides acting as glucokinase activators,” Tetrahedron Letters, vol. 47, no. 16, pp. 2675–2678, 2006, doi: 10.1016/j.tetlet.2006.02.110.

HEUSER, Stefan, David G. BARRETT, Martina BERG, Benjamin BONNIER, Astrid KAHL, Maria LUZ DE LA PUENTE, Niall ORAM, Rainer RIEDL, Ulrike ROETTIG, Gema Sanz GIL, Erich SEGER, David J. STEGGLES, Jutta WANNER und Andreas G. WEICHERT, 2006. Synthesis of novel cyclopropylic sulfones and sulfonamides acting as glucokinase activators. Tetrahedron Letters. 2006. Bd. 47, Nr. 16, S. 2675–2678. DOI 10.1016/j.tetlet.2006.02.110

Heuser, Stefan, David G. Barrett, Martina Berg, Benjamin Bonnier, Astrid Kahl, Maria Luz De La Puente, Niall Oram, et al. 2006. “Synthesis of Novel Cyclopropylic Sulfones and Sulfonamides Acting as Glucokinase Activators.” Tetrahedron Letters 47 (16): 2675–78. https://doi.org/10.1016/j.tetlet.2006.02.110.

Heuser, Stefan, et al. “Synthesis of Novel Cyclopropylic Sulfones and Sulfonamides Acting as Glucokinase Activators.” Tetrahedron Letters, vol. 47, no. 16, 2006, pp. 2675–78, https://doi.org/10.1016/j.tetlet.2006.02.110.