Please use this identifier to cite or link to this item: https://doi.org/10.21256/zhaw-26137
Publication type: Article in scientific journal
Type of review: Peer review (publication)
Title: Accompanied versus unaccompanied walking for continuous oxygen saturation measurement during 6-min walk test in COPD : a randomised crossover study
Authors: Riegler, Thomas F.
Frei, Anja
Haile, Sarah R.
Radtke, Thomas
et. al: No
DOI: 10.1183/23120541.00921-2020
10.21256/zhaw-26137
Published in: ERJ Open Research
Volume(Issue): 7
Issue: 3
Page(s): 921-2020
Issue Date: 2021
Publisher / Ed. Institution: European Respiratory Society
ISSN: 2312-0541
Language: English
Subjects: Physiotherapy; Biostatistic; Oxygen saturation; Walk; Chronic obstructive pulmonary disease (COPD)
Subject (DDC): 616: Internal medicine and diseases
Abstract: The aim of this study was to determine if there is a difference in 6-min walk test (6MWT) distance when the assessor accompanies the patient to continuously measure peripheral oxygen saturation (S pO2 ) compared to the patient walking unaccompanied. We conducted a randomised crossover study to evaluate the impact of the assessor walking with the patient during the 6MWT (6MWTwith) versus the patient walking alone (6MWTwithout). At the end of a pulmonary rehabilitation programme, each patient performed two 6MWTs in random order and separated by a 30-min rest. 49 patients with chronic obstructive pulmonary disease (COPD) (Global Initiative for Obstructive Lung Disease classification II-IV) were included. In a regression model adjusting for period and subject, accompanying the patient resulted in a lower walking distance (mean difference -9.1 m, 95% CI -13.9- -4.3, p=0.0004). Notably, six patients walked more than 30 m farther (minimal important difference) in one of the two conditions (6MWTwith: n=1, 6MWTwithout: n=5). There were no between-sequence-group differences in heart rate, dyspnoea, leg fatigue and S pO2 . The median (interquartile range) number and duration of S pO2 signal artefacts were high but not different between the experimental conditions (6MWTwith: 17 (4-24), 34 s (7-113 s); 6 MWTwithout: 11 (3-26), 24 s (4-62 s)). At a study population level, we observed a statistically significant difference in 6MWT distance between the two experimental conditions; however, the magnitude of difference was small and may not be clinically relevant. Nevertheless, in a clinical setting, unaccompanied walking resulted in a substantially higher walking distance in individual patients, pointing towards strictly standardised testing methodology, in particular in pre-post study designs.
URI: https://digitalcollection.zhaw.ch/handle/11475/26137
Fulltext version: Published version
License (according to publishing contract): CC BY-NC 4.0: Attribution - Non commercial 4.0 International
Departement: School of Health Sciences
Organisational Unit: Institute of Physiotherapy (IPT)
Appears in collections:Publikationen Gesundheit

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Riegler, T. F., Frei, A., Haile, S. R., & Radtke, T. (2021). Accompanied versus unaccompanied walking for continuous oxygen saturation measurement during 6-min walk test in COPD : a randomised crossover study. ERJ Open Research, 7(3), 921–2020. https://doi.org/10.1183/23120541.00921-2020
Riegler, T.F. et al. (2021) ‘Accompanied versus unaccompanied walking for continuous oxygen saturation measurement during 6-min walk test in COPD : a randomised crossover study’, ERJ Open Research, 7(3), pp. 921–2020. Available at: https://doi.org/10.1183/23120541.00921-2020.
T. F. Riegler, A. Frei, S. R. Haile, and T. Radtke, “Accompanied versus unaccompanied walking for continuous oxygen saturation measurement during 6-min walk test in COPD : a randomised crossover study,” ERJ Open Research, vol. 7, no. 3, pp. 921–2020, 2021, doi: 10.1183/23120541.00921-2020.
RIEGLER, Thomas F., Anja FREI, Sarah R. HAILE und Thomas RADTKE, 2021. Accompanied versus unaccompanied walking for continuous oxygen saturation measurement during 6-min walk test in COPD : a randomised crossover study. ERJ Open Research. 2021. Bd. 7, Nr. 3, S. 921–2020. DOI 10.1183/23120541.00921-2020
Riegler, Thomas F., Anja Frei, Sarah R. Haile, and Thomas Radtke. 2021. “Accompanied versus Unaccompanied Walking for Continuous Oxygen Saturation Measurement during 6-Min Walk Test in COPD : A Randomised Crossover Study.” ERJ Open Research 7 (3): 921–2020. https://doi.org/10.1183/23120541.00921-2020.
Riegler, Thomas F., et al. “Accompanied versus Unaccompanied Walking for Continuous Oxygen Saturation Measurement during 6-Min Walk Test in COPD : A Randomised Crossover Study.” ERJ Open Research, vol. 7, no. 3, 2021, pp. 921–2020, https://doi.org/10.1183/23120541.00921-2020.


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