Conversion in ASIA impairment scale during the first year after traumatic spinal cord injury

Spiess, Martina R.; Müller, Roland M.; Rupp, Rüdiger; Schuld, Christian; van Hedel, Hubertus

doi:10.1089/neu.2008.0760

Publication type:	Article in scientific journal
Type of review:	Peer review (publication)
Title:	Conversion in ASIA impairment scale during the first year after traumatic spinal cord injury
Authors:	Spiess, Martina R. Müller, Roland M. Rupp, Rüdiger Schuld, Christian van Hedel, Hubertus
et. al:	No
DOI:	10.1089/neu.2008.0760
Published in:	Journal of Neurotrauma
Volume(Issue):	26
Issue:	11
Page(s):	2027
Pages to:	2036
Issue Date:	Nov-2009
Publisher / Ed. Institution:	Mary Ann Liebert
ISSN:	0897-7151 1557-9042
Language:	English
Subjects:	Humans; Spinal cord injury; Time factor; Recovery of function; Severity of illness index
Subject (DDC):	616.8: Neurology, diseases of nervous system 617: Surgery
Abstract:	The neurological severity of a spinal cord injury (SCI) is commonly classified according to the American Spinal Injury Association (ASIA) Impairment Scale (AIS). The aim of this study was to assess the course of the AIS following SCI, and to discern the nature of any changes in the classification that occur. Assessments were performed in a European cohort of SCI patients within 2 weeks and at 1, 3, 6, and 12 months after the initial injury. Overall, about 70% of the patients initially diagnosed as AIS A did not convert, as did 90% of the AIS D patients. When only evaluating patients with complete datasets, 68% did not convert, while the AIS category improved in 30% of patients and deteriorated in 2%. A change in the last sacral segments (40%), motor improvement (31%), sensory improvement (19%), and a change in the neurological level of the SCI (10%) contributed to or accompanied the AIS conversion. When the AIS remained unchanged between successive assessment points, there was no change in the number of muscles graded three or more (NMG3(+)) in 73% of the transitions. An improvement in AIS was associated with a gain in NMG3(+) in 49% of the transitions, while an aggravation in AIS was accompanied by a loss in NMG3(+) in 10% of the transitions. These results, documenting a substantial amount of spontaneous AIS conversions, should be taken into consideration when designing clinical trials to assess the effects of potential new treatments for SCI.
URI:	https://digitalcollection.zhaw.ch/handle/11475/25606
Fulltext version:	Published version
License (according to publishing contract):	Licence according to publishing contract
Departement:	School of Health Sciences
Organisational Unit:	Institute of Occupational Therapy (IER)
Appears in collections:	Publikationen Gesundheit

Files in This Item:

There are no files associated with this item.

Show full item record

Spiess, M. R., Müller, R. M., Rupp, R., Schuld, C., & van Hedel, H. (2009). Conversion in ASIA impairment scale during the first year after traumatic spinal cord injury. Journal of Neurotrauma, 26(11), 2027–2036. https://doi.org/10.1089/neu.2008.0760

Spiess, M.R. et al. (2009) ‘Conversion in ASIA impairment scale during the first year after traumatic spinal cord injury’, Journal of Neurotrauma, 26(11), pp. 2027–2036. Available at: https://doi.org/10.1089/neu.2008.0760.

M. R. Spiess, R. M. Müller, R. Rupp, C. Schuld, and H. van Hedel, “Conversion in ASIA impairment scale during the first year after traumatic spinal cord injury,” Journal of Neurotrauma, vol. 26, no. 11, pp. 2027–2036, Nov. 2009, doi: 10.1089/neu.2008.0760.

SPIESS, Martina R., Roland M. MÜLLER, Rüdiger RUPP, Christian SCHULD und Hubertus VAN HEDEL, 2009. Conversion in ASIA impairment scale during the first year after traumatic spinal cord injury. Journal of Neurotrauma. November 2009. Bd. 26, Nr. 11, S. 2027–2036. DOI 10.1089/neu.2008.0760

Spiess, Martina R., Roland M. Müller, Rüdiger Rupp, Christian Schuld, and Hubertus van Hedel. 2009. “Conversion in ASIA Impairment Scale during the First Year after Traumatic Spinal Cord Injury.” Journal of Neurotrauma 26 (11): 2027–36. https://doi.org/10.1089/neu.2008.0760.

Spiess, Martina R., et al. “Conversion in ASIA Impairment Scale during the First Year after Traumatic Spinal Cord Injury.” Journal of Neurotrauma, vol. 26, no. 11, Nov. 2009, pp. 2027–36, https://doi.org/10.1089/neu.2008.0760.