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Please use this identifier to cite or link to this item: https://doi.org/10.21256/zhaw-1596
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dc.contributor.authorPietsch-Schmied, Constanze-
dc.contributor.authorKersten, Susanne-
dc.contributor.authorValenta, Hana-
dc.contributor.authorDänicke, Sven-
dc.contributor.authorSchulz, Carsten-
dc.contributor.authorBurkhardt-Holm, Patricia-
dc.contributor.authorJunge, Ranka-
dc.date.accessioned2018-01-31T10:48:00Z-
dc.date.available2018-01-31T10:48:00Z-
dc.date.issued2015-
dc.identifier.issn2072-6651de_CH
dc.identifier.urihttps://digitalcollection.zhaw.ch/handle/11475/2357-
dc.description.abstractThe mycotoxin zearalenone (ZEN) is frequently contaminating animal feeds including feed used in aquaculture. In the present study, the effects of dietary exposure to ZEN on carp (Cyprinus carpio L.) were investigated. ZEN at three different concentrations (low dose: 332 mg kg-1, medium dose: 621 mg kg-1 and high dose: 797 mg kg-1 final feed, respectively) was administered to juvenile carp for four weeks. Additional groups received the mycotoxin for the same time period but were fed with the uncontaminated diet for two more weeks to examine the reversibility of the ZEN effects. No effects on growth were observed during the feeding trial, but effects on haematological parameters occurred. In addition, an influence on white blood cell counts was noted whereby granulocytes and monocytes were affected in fish treated with the medium and high dose ZEN diet. In muscle samples, marginal ZEN and α-zearalenol (a-ZEL) concentrations were detected. Furthermore, the genotoxic potential of ZEN was confirmed by analysing formation of micronuclei in erythrocytes. In contrast to previous reports on other fish species estrogenic effects measured as vitellogenin concentrations in serum samples were not increased by dietary exposure to ZEN. This is probably due to the fact that ZEN is rapidly metabolized in carp.de_CH
dc.language.isoende_CH
dc.publisherMDPIde_CH
dc.relation.ispartofToxinsde_CH
dc.rightshttp://creativecommons.org/licenses/by/4.0/de_CH
dc.subjectBlood cell populationsde_CH
dc.subjectAquaculturede_CH
dc.subjectFeed qualityde_CH
dc.subjectGenotoxicityde_CH
dc.subject.ddc572: Biochemiede_CH
dc.titleEffects of dietary exposure to zearalenone (ZEN) on carp (Cyprinus carpio L.)de_CH
dc.typeBeitrag in wissenschaftlicher Zeitschriftde_CH
dcterms.typeTextde_CH
zhaw.departementLife Sciences und Facility Managementde_CH
zhaw.organisationalunitInstitut für Umwelt und Natürliche Ressourcen (IUNR)de_CH
dc.identifier.doi10.21256/zhaw-1596-
dc.identifier.doi10.3390/toxins7093465de_CH
zhaw.funding.euNode_CH
zhaw.issue9de_CH
zhaw.originated.zhawYesde_CH
zhaw.pages.end3480de_CH
zhaw.pages.start3465de_CH
zhaw.publication.statuspublishedVersionde_CH
zhaw.volume7de_CH
zhaw.publication.reviewPeer review (Publikation)de_CH
zhaw.webfeedAquakultur-Systemede_CH
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Pietsch-Schmied, C., Kersten, S., Valenta, H., Dänicke, S., Schulz, C., Burkhardt-Holm, P., & Junge, R. (2015). Effects of dietary exposure to zearalenone (ZEN) on carp (Cyprinus carpio L.). Toxins, 7(9), 3465–3480. https://doi.org/10.21256/zhaw-1596
Pietsch-Schmied, C. et al. (2015) ‘Effects of dietary exposure to zearalenone (ZEN) on carp (Cyprinus carpio L.)’, Toxins, 7(9), pp. 3465–3480. Available at: https://doi.org/10.21256/zhaw-1596.
C. Pietsch-Schmied et al., “Effects of dietary exposure to zearalenone (ZEN) on carp (Cyprinus carpio L.),” Toxins, vol. 7, no. 9, pp. 3465–3480, 2015, doi: 10.21256/zhaw-1596.
PIETSCH-SCHMIED, Constanze, Susanne KERSTEN, Hana VALENTA, Sven DÄNICKE, Carsten SCHULZ, Patricia BURKHARDT-HOLM und Ranka JUNGE, 2015. Effects of dietary exposure to zearalenone (ZEN) on carp (Cyprinus carpio L.). Toxins. 2015. Bd. 7, Nr. 9, S. 3465–3480. DOI 10.21256/zhaw-1596
Pietsch-Schmied, Constanze, Susanne Kersten, Hana Valenta, Sven Dänicke, Carsten Schulz, Patricia Burkhardt-Holm, and Ranka Junge. 2015. “Effects of Dietary Exposure to Zearalenone (ZEN) on Carp (Cyprinus Carpio L.).” Toxins 7 (9): 3465–80. https://doi.org/10.21256/zhaw-1596.
Pietsch-Schmied, Constanze, et al. “Effects of Dietary Exposure to Zearalenone (ZEN) on Carp (Cyprinus Carpio L.).” Toxins, vol. 7, no. 9, 2015, pp. 3465–80, https://doi.org/10.21256/zhaw-1596.


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