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dc.contributor.authorDittler, Ina-
dc.contributor.authorKaiser, Stephan-
dc.contributor.authorBlaschczok, Katharina-
dc.contributor.authorLöffelholz, Christian-
dc.contributor.authorBösch, Pascal-
dc.contributor.authorDornfeld, Wolfgang-
dc.contributor.authorSchöb, Reto-
dc.contributor.authorRojahn, Jürgen-
dc.contributor.authorKraume, Matthias-
dc.contributor.authorEibl, Dieter-
dc.date.accessioned2018-01-31T10:21:16Z-
dc.date.available2018-01-31T10:21:16Z-
dc.date.issued2014-05-
dc.identifier.issn1618-0240de_CH
dc.identifier.issn1618-2863de_CH
dc.identifier.urihttps://digitalcollection.zhaw.ch/handle/11475/2344-
dc.description.abstractThe suitability of oil-water emulsions to predict shear forces in stirred bioreactors under cost-effective and time-saving conditions has been demonstrated several times, but no application to pumps has been described so far. In this report, the drop sizes in a model oil-water system were determined for the Levitronix PuraLev® MU series (PuraLev® 200MU and PuraLev® 600MU), a peristaltic pump (Masterflex® I/P Easy Load), and a 4-piston diaphragm pump (Quattroflow 1200-SU) using inline endoscopy. It was determined that the Sauter mean diameter could be used as a comparison criterion to estimate mechanical stress in pumps. The investigation showed that PuraLev® MU pumps are characterized by up to 59 % larger Sauter mean diameters than their counterparts at comparable operational conditions. This indicates lower hydrodynamic stress in the PuraLev® MU pumps. Using computational fluid dynamics (CFD), a well-streamlined fluid flow and low turbulent energy dissipation rates (TEDR) were found in the PuraLev® MU pumps, which correlated well with experimental results. A calculation model was used to predict the Sauter mean diameter by combining both experimental and CFD data. Good agreement with deviations below 13% was determined between model predictions and experimental data.de_CH
dc.language.isoende_CH
dc.publisherWileyde_CH
dc.relation.ispartofEngineering in Life Sciencesde_CH
dc.rightsLicence according to publishing contractde_CH
dc.subject.ddc620: Ingenieurwesende_CH
dc.titleA cost-effective and reliable method to predict mechanical stress in single-use and standard pumpsde_CH
dc.typeBeitrag in wissenschaftlicher Zeitschriftde_CH
dcterms.typeTextde_CH
zhaw.departementLife Sciences und Facility Managementde_CH
zhaw.organisationalunitInstitut für Chemie und Biotechnologie (ICBT)de_CH
zhaw.publisher.placeWeinheimde_CH
dc.identifier.doi10.1002/elsc.201300068de_CH
zhaw.funding.euNode_CH
zhaw.issue3de_CH
zhaw.originated.zhawYesde_CH
zhaw.pages.end317de_CH
zhaw.pages.start311de_CH
zhaw.publication.statuspublishedVersionde_CH
zhaw.volume14de_CH
zhaw.publication.reviewPeer review (Publikation)de_CH
Appears in collections:Publikationen Life Sciences und Facility Management

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Dittler, I., Kaiser, S., Blaschczok, K., Löffelholz, C., Bösch, P., Dornfeld, W., Schöb, R., Rojahn, J., Kraume, M., & Eibl, D. (2014). A cost-effective and reliable method to predict mechanical stress in single-use and standard pumps. Engineering in Life Sciences, 14(3), 311–317. https://doi.org/10.1002/elsc.201300068
Dittler, I. et al. (2014) ‘A cost-effective and reliable method to predict mechanical stress in single-use and standard pumps’, Engineering in Life Sciences, 14(3), pp. 311–317. Available at: https://doi.org/10.1002/elsc.201300068.
I. Dittler et al., “A cost-effective and reliable method to predict mechanical stress in single-use and standard pumps,” Engineering in Life Sciences, vol. 14, no. 3, pp. 311–317, May 2014, doi: 10.1002/elsc.201300068.
DITTLER, Ina, Stephan KAISER, Katharina BLASCHCZOK, Christian LÖFFELHOLZ, Pascal BÖSCH, Wolfgang DORNFELD, Reto SCHÖB, Jürgen ROJAHN, Matthias KRAUME und Dieter EIBL, 2014. A cost-effective and reliable method to predict mechanical stress in single-use and standard pumps. Engineering in Life Sciences. Mai 2014. Bd. 14, Nr. 3, S. 311–317. DOI 10.1002/elsc.201300068
Dittler, Ina, Stephan Kaiser, Katharina Blaschczok, Christian Löffelholz, Pascal Bösch, Wolfgang Dornfeld, Reto Schöb, Jürgen Rojahn, Matthias Kraume, and Dieter Eibl. 2014. “A Cost-Effective and Reliable Method to Predict Mechanical Stress in Single-Use and Standard Pumps.” Engineering in Life Sciences 14 (3): 311–17. https://doi.org/10.1002/elsc.201300068.
Dittler, Ina, et al. “A Cost-Effective and Reliable Method to Predict Mechanical Stress in Single-Use and Standard Pumps.” Engineering in Life Sciences, vol. 14, no. 3, May 2014, pp. 311–17, https://doi.org/10.1002/elsc.201300068.


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