Please use this identifier to cite or link to this item: https://doi.org/10.21256/zhaw-21999
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dc.contributor.authorKhojasteh, Abbas-
dc.contributor.authorMirjalili, Mohammad Hossein-
dc.contributor.authorAlcalde, Miguel Angel-
dc.contributor.authorCusido, Rosa M.-
dc.contributor.authorEibl, Regine-
dc.contributor.authorPalazon, Javier-
dc.date.accessioned2021-03-14T11:33:06Z-
dc.date.available2021-03-14T11:33:06Z-
dc.date.issued2020-
dc.identifier.issn2076-3921de_CH
dc.identifier.urihttps://digitalcollection.zhaw.ch/handle/11475/21999-
dc.description.abstractModern lifestyle factors, such as physical inactivity, obesity, smoking, and exposure to environmental pollution, induce excessive generation of free radicals and reactive oxygen species (ROS) in the body. These by-products of oxygen metabolism play a key role in the development of various human diseases such as cancer, diabetes, heart failure, brain damage, muscle problems, premature aging, eye injuries, and a weakened immune system. Synthetic and natural antioxidants, which act as free radical scavengers, are widely used in the food and beverage industries. The toxicity and carcinogenic effects of some synthetic antioxidants have generated interest in natural alternatives, especially plant-derived polyphenols (e.g., phenolic acids, flavonoids, stilbenes, tannins, coumarins, lignins, lignans, quinines, curcuminoids, chalcones, and essential oil terpenoids). This review focuses on the well-known phenolic antioxidant rosmarinic acid (RA), an ester of caffeic acid and (R)-(+)-3-(3,4-dihydroxyphenyl) lactic acid, describing its wide distribution in thirty-nine plant families and the potential productivity of plant sources. A botanical and phytochemical description is provided of a new rich source of RA, Satureja khuzistanica Jamzad (Lamiaceae). Recently reported approaches to the biotechnological production of RA are summarized, highlighting the establishment of cell suspension cultures of S. khuzistanica as an RA chemical biofactory.de_CH
dc.language.isoende_CH
dc.publisherMDPIde_CH
dc.relation.ispartofAntioxidantsde_CH
dc.rightshttp://creativecommons.org/licenses/by/4.0/de_CH
dc.subjectCell culturesde_CH
dc.subjectLamiaceaede_CH
dc.subjectOxidative stressde_CH
dc.subjectPhenolic compoundde_CH
dc.subjectRosmarinic acidde_CH
dc.subjectSavoryde_CH
dc.subject.ddc610.28: Biomedizin, Biomedizinische Technikde_CH
dc.titlePowerful plant antioxidants : a new biosustainable approach to the production of rosmarinic acidde_CH
dc.typeBeitrag in wissenschaftlicher Zeitschriftde_CH
dcterms.typeTextde_CH
zhaw.departementLife Sciences und Facility Managementde_CH
zhaw.organisationalunitInstitut für Chemie und Biotechnologie (ICBT)de_CH
dc.identifier.doi10.3390/antiox9121273de_CH
dc.identifier.doi10.21256/zhaw-21999-
dc.identifier.pmid33327619de_CH
zhaw.funding.euNode_CH
zhaw.issue12de_CH
zhaw.originated.zhawYesde_CH
zhaw.pages.start1273de_CH
zhaw.publication.statuspublishedVersionde_CH
zhaw.volume9de_CH
zhaw.publication.reviewPeer review (Publikation)de_CH
zhaw.author.additionalNode_CH
zhaw.display.portraitYesde_CH
Appears in collections:Publikationen Life Sciences und Facility Management

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