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Please use this identifier to cite or link to this item: https://doi.org/10.21256/zhaw-21977
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dc.contributor.authorSeiler, Annina-
dc.contributor.authorBlum, David-
dc.contributor.authorHertler, Caroline-
dc.contributor.authorSchettle, Markus-
dc.contributor.authorZipser, Carl Moritz-
dc.contributor.authorBode, Leonie-
dc.contributor.authorGehrke, Samuel-
dc.contributor.authorErnst, Jutta-
dc.contributor.authorSchubert, Maria-
dc.contributor.authorvon Känel, Roland-
dc.contributor.authorBoettger, Soenke-
dc.date.accessioned2021-03-12T14:37:39Z-
dc.date.available2021-03-12T14:37:39Z-
dc.date.issued2020-
dc.identifier.issn1478-9515de_CH
dc.identifier.issn1478-9523de_CH
dc.identifier.urihttps://digitalcollection.zhaw.ch/handle/11475/21977-
dc.descriptionErworben im Rahmen der Schweizer Nationallizenzen (http://www.nationallizenzen.ch) A corrigendum to this article was published in Palliative & Supportive Care 19(3), June 2021, pp. 393. https://doi.org/10.1017/S1478951521000560de_CH
dc.description.abstractObjectives: Patients with terminal illness are at high risk of developing delirium, in particular, those with multiple predisposing and precipitating risk factors. Delirium in palliative care is largely under-researched, and few studies have systematically assessed key aspects of delirium in elderly, palliative-care patients. Methods: In this prospective, observational cohort study at a tertiary care center, 229 delirious palliative-care patients stratified by age: <65 (N = 105) and ≥65 years (N = 124), were analyzed with logistic regression models to identify associations with respect to predisposing and precipitating factors. Results: In 88% of the patients, the underlying diagnosis was cancer. Mortality rate and median time to death did not differ significantly between the two age groups. No intergroup differences were detected with respect to gender, care requirements, length of hospital stay, or medical costs. In patients ≥65 years, exclusively predisposing factors were relevant for delirium, including hearing impairment [odds ratio (OR) 3.64; confidence interval (CI) 1.90– 6.99; P < 0.001], hypertonia (OR 3.57; CI 1.84–6.92; P < 0.001), and chronic kidney disease (OR 4.84; CI 1.19–19.72; P = 0.028). In contrast, in patients <65 years, only precipitating factors were relevant for delirium, including cerebral edema (OR 0.02; CI 0.01–0.43; P = 0.012). Significance of results: The results of this study demonstrate that death in delirious palliativecare patients occurs irrespective of age. The multifactorial nature and adverse outcomes of delirium across all age in these patients require clinical recognition. Potentially reversible factors should be detected early to prevent or mitigate delirium and its poor survival outcomes.de_CH
dc.language.isoende_CH
dc.publisherCambridge University Pressde_CH
dc.relation.ispartofPalliative & Supportive Carede_CH
dc.rightsLicence according to publishing contractde_CH
dc.subjectDeliriumde_CH
dc.subjectPalliative-care patientde_CH
dc.subjectPrecipitating factorde_CH
dc.subjectPredisposing factorde_CH
dc.subject.ddc616.8: Neurologie und Krankheiten des Nervensystemsde_CH
dc.titleDeath in delirious palliative-care patients occurs irrespective of age : a prospective, observational cohort study of 229 delirious palliative-care patientsde_CH
dc.typeBeitrag in wissenschaftlicher Zeitschriftde_CH
dcterms.typeTextde_CH
zhaw.departementGesundheitde_CH
zhaw.organisationalunitInstitut für Pflege (IPF)de_CH
dc.identifier.doi10.1017/S1478951520000887de_CH
dc.identifier.doi10.21256/zhaw-21977-
dc.identifier.pmid32928325de_CH
zhaw.funding.euNode_CH
zhaw.issue3de_CH
zhaw.originated.zhawYesde_CH
zhaw.pages.end282de_CH
zhaw.pages.start274de_CH
zhaw.publication.statuspublishedVersionde_CH
zhaw.volume19de_CH
zhaw.embargo.end2027-01-01de_CH
zhaw.publication.reviewPeer review (Publikation)de_CH
zhaw.author.additionalYesde_CH
zhaw.display.portraitYesde_CH
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Seiler, A., Blum, D., Hertler, C., Schettle, M., Zipser, C. M., Bode, L., Gehrke, S., Ernst, J., Schubert, M., von Känel, R., & Boettger, S. (2020). Death in delirious palliative-care patients occurs irrespective of age : a prospective, observational cohort study of 229 delirious palliative-care patients. Palliative & Supportive Care, 19(3), 274–282. https://doi.org/10.1017/S1478951520000887
Seiler, A. et al. (2020) ‘Death in delirious palliative-care patients occurs irrespective of age : a prospective, observational cohort study of 229 delirious palliative-care patients’, Palliative & Supportive Care, 19(3), pp. 274–282. Available at: https://doi.org/10.1017/S1478951520000887.
A. Seiler et al., “Death in delirious palliative-care patients occurs irrespective of age : a prospective, observational cohort study of 229 delirious palliative-care patients,” Palliative & Supportive Care, vol. 19, no. 3, pp. 274–282, 2020, doi: 10.1017/S1478951520000887.
SEILER, Annina, David BLUM, Caroline HERTLER, Markus SCHETTLE, Carl Moritz ZIPSER, Leonie BODE, Samuel GEHRKE, Jutta ERNST, Maria SCHUBERT, Roland VON KÄNEL und Soenke BOETTGER, 2020. Death in delirious palliative-care patients occurs irrespective of age : a prospective, observational cohort study of 229 delirious palliative-care patients. Palliative & Supportive Care. 2020. Bd. 19, Nr. 3, S. 274–282. DOI 10.1017/S1478951520000887
Seiler, Annina, David Blum, Caroline Hertler, Markus Schettle, Carl Moritz Zipser, Leonie Bode, Samuel Gehrke, et al. 2020. “Death in Delirious Palliative-Care Patients Occurs Irrespective of Age : A Prospective, Observational Cohort Study of 229 Delirious Palliative-Care Patients.” Palliative & Supportive Care 19 (3): 274–82. https://doi.org/10.1017/S1478951520000887.
Seiler, Annina, et al. “Death in Delirious Palliative-Care Patients Occurs Irrespective of Age : A Prospective, Observational Cohort Study of 229 Delirious Palliative-Care Patients.” Palliative & Supportive Care, vol. 19, no. 3, 2020, pp. 274–82, https://doi.org/10.1017/S1478951520000887.


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