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https://doi.org/10.21256/zhaw-21977| Publikationstyp: | Beitrag in wissenschaftlicher Zeitschrift |
| Art der Begutachtung: | Peer review (Publikation) |
| Titel: | Death in delirious palliative-care patients occurs irrespective of age : a prospective, observational cohort study of 229 delirious palliative-care patients |
| Autor/-in: | Seiler, Annina Blum, David Hertler, Caroline Schettle, Markus Zipser, Carl Moritz Bode, Leonie Gehrke, Samuel Ernst, Jutta Schubert, Maria von Känel, Roland Boettger, Soenke |
| et. al: | Yes |
| DOI: | 10.1017/S1478951520000887 10.21256/zhaw-21977 |
| Erschienen in: | Palliative & Supportive Care |
| Band(Heft): | 19 |
| Heft: | 3 |
| Seite(n): | 274 |
| Seiten bis: | 282 |
| Erscheinungsdatum: | 2020 |
| Verlag / Hrsg. Institution: | Cambridge University Press |
| ISSN: | 1478-9515 1478-9523 |
| Sprache: | Englisch |
| Schlagwörter: | Delirium; Palliative-care patient; Precipitating factor; Predisposing factor |
| Fachgebiet (DDC): | 616.8: Neurologie und Krankheiten des Nervensystems |
| Zusammenfassung: | Objectives: Patients with terminal illness are at high risk of developing delirium, in particular, those with multiple predisposing and precipitating risk factors. Delirium in palliative care is largely under-researched, and few studies have systematically assessed key aspects of delirium in elderly, palliative-care patients. Methods: In this prospective, observational cohort study at a tertiary care center, 229 delirious palliative-care patients stratified by age: <65 (N = 105) and ≥65 years (N = 124), were analyzed with logistic regression models to identify associations with respect to predisposing and precipitating factors. Results: In 88% of the patients, the underlying diagnosis was cancer. Mortality rate and median time to death did not differ significantly between the two age groups. No intergroup differences were detected with respect to gender, care requirements, length of hospital stay, or medical costs. In patients ≥65 years, exclusively predisposing factors were relevant for delirium, including hearing impairment [odds ratio (OR) 3.64; confidence interval (CI) 1.90– 6.99; P < 0.001], hypertonia (OR 3.57; CI 1.84–6.92; P < 0.001), and chronic kidney disease (OR 4.84; CI 1.19–19.72; P = 0.028). In contrast, in patients <65 years, only precipitating factors were relevant for delirium, including cerebral edema (OR 0.02; CI 0.01–0.43; P = 0.012). Significance of results: The results of this study demonstrate that death in delirious palliativecare patients occurs irrespective of age. The multifactorial nature and adverse outcomes of delirium across all age in these patients require clinical recognition. Potentially reversible factors should be detected early to prevent or mitigate delirium and its poor survival outcomes. |
| Weitere Angaben: | Erworben im Rahmen der Schweizer Nationallizenzen (http://www.nationallizenzen.ch) A corrigendum to this article was published in Palliative & Supportive Care 19(3), June 2021, pp. 393. https://doi.org/10.1017/S1478951521000560 |
| URI: | https://digitalcollection.zhaw.ch/handle/11475/21977 |
| Volltext Version: | Publizierte Version |
| Lizenz (gemäss Verlagsvertrag): | Lizenz gemäss Verlagsvertrag |
| Gesperrt bis: | 2027-01-01 |
| Departement: | Gesundheit |
| Organisationseinheit: | Institut für Pflege (IPF) |
| Enthalten in den Sammlungen: | Publikationen Gesundheit |
Dateien zu dieser Ressource:
| Datei | Beschreibung | Größe | Format | |
|---|---|---|---|---|
| 2021_Seiler-etal_Death-in-delirious-palliative-care-patients.pdf Bis 2027-01-01 | 563.1 kB | Adobe PDF | Öffnen/Anzeigen |
Zur Langanzeige
Seiler, A., Blum, D., Hertler, C., Schettle, M., Zipser, C. M., Bode, L., Gehrke, S., Ernst, J., Schubert, M., von Känel, R., & Boettger, S. (2020). Death in delirious palliative-care patients occurs irrespective of age : a prospective, observational cohort study of 229 delirious palliative-care patients. Palliative & Supportive Care, 19(3), 274–282. https://doi.org/10.1017/S1478951520000887
Seiler, A. et al. (2020) ‘Death in delirious palliative-care patients occurs irrespective of age : a prospective, observational cohort study of 229 delirious palliative-care patients’, Palliative & Supportive Care, 19(3), pp. 274–282. Available at: https://doi.org/10.1017/S1478951520000887.
A. Seiler et al., “Death in delirious palliative-care patients occurs irrespective of age : a prospective, observational cohort study of 229 delirious palliative-care patients,” Palliative & Supportive Care, vol. 19, no. 3, pp. 274–282, 2020, doi: 10.1017/S1478951520000887.
SEILER, Annina, David BLUM, Caroline HERTLER, Markus SCHETTLE, Carl Moritz ZIPSER, Leonie BODE, Samuel GEHRKE, Jutta ERNST, Maria SCHUBERT, Roland VON KÄNEL und Soenke BOETTGER, 2020. Death in delirious palliative-care patients occurs irrespective of age : a prospective, observational cohort study of 229 delirious palliative-care patients. Palliative & Supportive Care. 2020. Bd. 19, Nr. 3, S. 274–282. DOI 10.1017/S1478951520000887
Seiler, Annina, David Blum, Caroline Hertler, Markus Schettle, Carl Moritz Zipser, Leonie Bode, Samuel Gehrke, et al. 2020. “Death in Delirious Palliative-Care Patients Occurs Irrespective of Age : A Prospective, Observational Cohort Study of 229 Delirious Palliative-Care Patients.” Palliative & Supportive Care 19 (3): 274–82. https://doi.org/10.1017/S1478951520000887.
Seiler, Annina, et al. “Death in Delirious Palliative-Care Patients Occurs Irrespective of Age : A Prospective, Observational Cohort Study of 229 Delirious Palliative-Care Patients.” Palliative & Supportive Care, vol. 19, no. 3, 2020, pp. 274–82, https://doi.org/10.1017/S1478951520000887.
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