Please use this identifier to cite or link to this item: https://doi.org/10.21256/zhaw-20585
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dc.contributor.authorWade-Bohleber, Laura Maria-
dc.contributor.authorThoma, R.-
dc.contributor.authorGerber, A.J.-
dc.date.accessioned2020-10-14T11:15:45Z-
dc.date.available2020-10-14T11:15:45Z-
dc.date.issued2020-09-10-
dc.identifier.issn0925-4927de_CH
dc.identifier.issn1872-7506de_CH
dc.identifier.urihttps://digitalcollection.zhaw.ch/handle/11475/20585-
dc.description.abstractAberrant emotion processing is a core characteristic of panic disorder (PD). Findings concerning the underlying neural pathways remain inconsistent. We applied functional magnetic resonance imaging (fMRI) in the context of a task based on the circumplex model of affect. This model links affective states to two underlying neurophysiological systems: arousal and valence. Twenty-two healthy participants and 20 participants with PD rated arousal and valence in response to affective faces during fMRI. In healthy controls, we found that arousal modulated the hemodynamic response in the parahippocampus, the ventromedial prefrontal cortex and the cuneus during face perception. Valence and extreme ratings of valence modulated the hemodynamic response in temporal, parietal, somatosensory, premotor and cerebellar regions. Comparing healthy controls to participants with PD, we found that healthy controls showed a stronger modulation of the hemodynamic response during face perception associated with extreme ratings of valence in the parahippocampus and the supplementary motor area. This suggests parahippocampal dysfunction in the processing of highly valenced affective faces in PD, which may underlie aberrant contextualization of strong affective stimuli. Our findings need to be interpreted with care as they were adjusted for multiple comparisons using a liberal correction procedure.de_CH
dc.language.isoende_CH
dc.publisherElsevierde_CH
dc.relation.ispartofPsychiatry Research: Neuroimagingde_CH
dc.rightshttp://creativecommons.org/licenses/by-nc-nd/4.0/de_CH
dc.subjectAffective facesde_CH
dc.subjectCircumplex model of affectde_CH
dc.subjectFunctional magnetic resonance imagingde_CH
dc.subjectPanic disorderde_CH
dc.subject.ddc616.8: Neurologie und Krankheiten des Nervensystemsde_CH
dc.titleNeural correlates of subjective arousal and valence in health and panic disorderde_CH
dc.typeBeitrag in wissenschaftlicher Zeitschriftde_CH
dcterms.typeTextde_CH
zhaw.departementAngewandte Psychologiede_CH
zhaw.organisationalunitPsychologisches Institut (PI)de_CH
dc.identifier.doi10.1016/j.pscychresns.2020.111186de_CH
dc.identifier.doi10.21256/zhaw-20585-
dc.identifier.pmid32957042de_CH
zhaw.funding.euNode_CH
zhaw.issue111186de_CH
zhaw.originated.zhawYesde_CH
zhaw.publication.statuspublishedVersionde_CH
zhaw.volume305de_CH
zhaw.publication.reviewPeer review (Publikation)de_CH
zhaw.author.additionalNode_CH
zhaw.display.portraitYesde_CH
Appears in collections:Publikationen Angewandte Psychologie

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Wade-Bohleber, L. M., Thoma, R., & Gerber, A. J. (2020). Neural correlates of subjective arousal and valence in health and panic disorder. Psychiatry Research: Neuroimaging, 305(111186). https://doi.org/10.1016/j.pscychresns.2020.111186
Wade-Bohleber, L.M., Thoma, R. and Gerber, A.J. (2020) ‘Neural correlates of subjective arousal and valence in health and panic disorder’, Psychiatry Research: Neuroimaging, 305(111186). Available at: https://doi.org/10.1016/j.pscychresns.2020.111186.
L. M. Wade-Bohleber, R. Thoma, and A. J. Gerber, “Neural correlates of subjective arousal and valence in health and panic disorder,” Psychiatry Research: Neuroimaging, vol. 305, no. 111186, Sep. 2020, doi: 10.1016/j.pscychresns.2020.111186.
WADE-BOHLEBER, Laura Maria, R. THOMA und A.J. GERBER, 2020. Neural correlates of subjective arousal and valence in health and panic disorder. Psychiatry Research: Neuroimaging. 10 September 2020. Bd. 305, Nr. 111186. DOI 10.1016/j.pscychresns.2020.111186
Wade-Bohleber, Laura Maria, R. Thoma, and A.J. Gerber. 2020. “Neural Correlates of Subjective Arousal and Valence in Health and Panic Disorder.” Psychiatry Research: Neuroimaging 305 (111186). https://doi.org/10.1016/j.pscychresns.2020.111186.
Wade-Bohleber, Laura Maria, et al. “Neural Correlates of Subjective Arousal and Valence in Health and Panic Disorder.” Psychiatry Research: Neuroimaging, vol. 305, no. 111186, Sept. 2020, https://doi.org/10.1016/j.pscychresns.2020.111186.


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