Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Schenk, A | - |
dc.contributor.author | Ziegler, LN | - |
dc.contributor.author | Meier, Nadja | - |
dc.contributor.author | Peter, Samuel | - |
dc.contributor.author | Wolfram, Evelyn | - |
dc.date.accessioned | 2018-01-10T13:00:10Z | - |
dc.date.available | 2018-01-10T13:00:10Z | - |
dc.date.issued | 2017-10-24 | - |
dc.identifier.issn | 2509-6656 | de_CH |
dc.identifier.uri | https://digitalcollection.zhaw.ch/handle/11475/1964 | - |
dc.description.abstract | Using a coreshell column, the new UHPLC-DAD method allows almost a baseline separation of seven sennosides and the monomeric hydroxyanthracene glycosides rhein 8-glycoside and aloe emodin 8-glycoside in senna pod dry extract and in a senna-fig syrup preparation. UV and mass spectrometry studies show that none of the peaks of interest is underlaid by flavonoids, a fact which, in the case of other LC methods for sennosides, requires a sample processing by means of SPE. Sennosides are determined by sennoside B, monomeric hydroyanthracene glycosides by rhein 8-glycoside as external standard. The combined determination of all hyrdoxyanthracene glycosides is important for pharmaceutical stability testing because sennosides are partly degraded to rhein- and aloe emodin 8-glycoside. In the posterior part of the chromatogram the aglycones rhein and aloe emodine can be determined. The complete assay runs 19 min. | de_CH |
dc.language.iso | en | de_CH |
dc.publisher | Thieme | de_CH |
dc.relation.ispartof | Planta Medica International Open | de_CH |
dc.rights | Licence according to publishing contract | de_CH |
dc.subject.ddc | 572: Biochemie | de_CH |
dc.subject.ddc | 615: Pharmakologie und Therapeutik | de_CH |
dc.subject.ddc | 660.6: Biotechnologie | de_CH |
dc.title | Combined determination of sennosides, monomeric hydroxyanthacene glycosides and anthraquinone aglycones by UHPLC-DAD | de_CH |
dc.type | Konferenz: Poster | de_CH |
dcterms.type | Text | de_CH |
zhaw.departement | Life Sciences und Facility Management | de_CH |
zhaw.organisationalunit | Institut für Chemie und Biotechnologie (ICBT) | de_CH |
dc.identifier.doi | 10.1055/s-0037-1608215 | de_CH |
zhaw.conference.details | 65th International Congress and Annual Meeting of the Society for Medicinal Plant and Natural Product Research (GA 2017), Basel, 3-6 September 2017 | de_CH |
zhaw.funding.eu | No | de_CH |
zhaw.originated.zhaw | Yes | de_CH |
zhaw.publication.status | publishedVersion | de_CH |
zhaw.volume | 4 | de_CH |
zhaw.publication.review | Peer review (Abstract) | de_CH |
zhaw.webfeed | Phytopharmazie | de_CH |
Appears in collections: | Publikationen Life Sciences und Facility Management |
Files in This Item:
There are no files associated with this item.
Show simple item record
Schenk, A., Ziegler, L., Meier, N., Peter, S., & Wolfram, E. (2017). Combined determination of sennosides, monomeric hydroxyanthacene glycosides and anthraquinone aglycones by UHPLC-DAD [Conference poster]. Planta Medica International Open, 4. https://doi.org/10.1055/s-0037-1608215
Schenk, A. et al. (2017) ‘Combined determination of sennosides, monomeric hydroxyanthacene glycosides and anthraquinone aglycones by UHPLC-DAD’, in Planta Medica International Open. Thieme. Available at: https://doi.org/10.1055/s-0037-1608215.
A. Schenk, L. Ziegler, N. Meier, S. Peter, and E. Wolfram, “Combined determination of sennosides, monomeric hydroxyanthacene glycosides and anthraquinone aglycones by UHPLC-DAD,” in Planta Medica International Open, Oct. 2017, vol. 4. doi: 10.1055/s-0037-1608215.
SCHENK, A, LN ZIEGLER, Nadja MEIER, Samuel PETER und Evelyn WOLFRAM, 2017. Combined determination of sennosides, monomeric hydroxyanthacene glycosides and anthraquinone aglycones by UHPLC-DAD. In: Planta Medica International Open. Conference poster. Thieme. 24 Oktober 2017
Schenk, A, LN Ziegler, Nadja Meier, Samuel Peter, and Evelyn Wolfram. 2017. “Combined Determination of Sennosides, Monomeric Hydroxyanthacene Glycosides and Anthraquinone Aglycones by UHPLC-DAD.” Conference poster. In Planta Medica International Open. Vol. 4. Thieme. https://doi.org/10.1055/s-0037-1608215.
Schenk, A., et al. “Combined Determination of Sennosides, Monomeric Hydroxyanthacene Glycosides and Anthraquinone Aglycones by UHPLC-DAD.” Planta Medica International Open, vol. 4, Thieme, 2017, https://doi.org/10.1055/s-0037-1608215.
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.