Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Voss, Moritz | - |
dc.contributor.author | Honda Malca, Sumire | - |
dc.contributor.author | Buller, Rebecca | - |
dc.date.accessioned | 2020-01-29T09:52:16Z | - |
dc.date.available | 2020-01-29T09:52:16Z | - |
dc.date.issued | 2020-01-22 | - |
dc.identifier.issn | 0947-6539 | de_CH |
dc.identifier.issn | 1521-3765 | de_CH |
dc.identifier.uri | https://digitalcollection.zhaw.ch/handle/11475/19230 | - |
dc.description.abstract | Freestanding non-heme iron halogenases are α-ketoglutarate dependent oxidoreductases that catalyze the installation of halogen atoms into unactivated sp 3 -hybridized carbon centers with high stereo- and regioselectivity. Since their discovery in 2014, a small number of indole-alkaloid and amino acid halogenases have been identified and characterized. First enzyme engineering examples suggest that the accessible substrate range of these enzymes may be expanded through the use of rational enzyme design and directed evolution. Structural investigations of non-heme iron halogenases acting of freestanding as well as tethered substrate are beginning to inform about the principles of the underlying halogenation mechanism. | de_CH |
dc.language.iso | en | de_CH |
dc.publisher | Wiley | de_CH |
dc.relation.ispartof | Chemistry - A European Journal | de_CH |
dc.rights | Licence according to publishing contract | de_CH |
dc.subject | C-H activation | de_CH |
dc.subject | Fe/ αKG-dependent Halogenases | de_CH |
dc.subject | Biocatalysis | de_CH |
dc.subject | Enzyme Engineering | de_CH |
dc.subject | Genome Mining | de_CH |
dc.subject.ddc | 660.6: Biotechnologie | de_CH |
dc.title | Exploring the biocatalytic potential of Fe/α‐ketoglutarate dependent halogenases | de_CH |
dc.type | Beitrag in wissenschaftlicher Zeitschrift | de_CH |
dcterms.type | Text | de_CH |
zhaw.departement | Life Sciences und Facility Management | de_CH |
zhaw.organisationalunit | Institut für Chemie und Biotechnologie (ICBT) | de_CH |
dc.identifier.doi | 10.1002/chem.201905752 | de_CH |
dc.identifier.pmid | 31968136 | de_CH |
zhaw.funding.eu | No | de_CH |
zhaw.originated.zhaw | Yes | de_CH |
zhaw.publication.status | publishedVersion | de_CH |
zhaw.publication.review | Peer review (Publikation) | de_CH |
zhaw.webfeed | Biokatalyse | de_CH |
zhaw.author.additional | No | de_CH |
Appears in collections: | Publikationen Life Sciences und Facility Management |
Files in This Item:
There are no files associated with this item.
Show simple item record
Voss, M., Honda Malca, S., & Buller, R. (2020). Exploring the biocatalytic potential of Fe/α‐ketoglutarate dependent halogenases. Chemistry - A European Journal. https://doi.org/10.1002/chem.201905752
Voss, M., Honda Malca, S. and Buller, R. (2020) ‘Exploring the biocatalytic potential of Fe/α‐ketoglutarate dependent halogenases’, Chemistry - A European Journal [Preprint]. Available at: https://doi.org/10.1002/chem.201905752.
M. Voss, S. Honda Malca, and R. Buller, “Exploring the biocatalytic potential of Fe/α‐ketoglutarate dependent halogenases,” Chemistry - A European Journal, Jan. 2020, doi: 10.1002/chem.201905752.
VOSS, Moritz, Sumire HONDA MALCA und Rebecca BULLER, 2020. Exploring the biocatalytic potential of Fe/α‐ketoglutarate dependent halogenases. Chemistry - A European Journal. 22 Januar 2020. DOI 10.1002/chem.201905752
Voss, Moritz, Sumire Honda Malca, and Rebecca Buller. 2020. “Exploring the Biocatalytic Potential of Fe/α‐Ketoglutarate Dependent Halogenases.” Chemistry - A European Journal, January. https://doi.org/10.1002/chem.201905752.
Voss, Moritz, et al. “Exploring the Biocatalytic Potential of Fe/α‐Ketoglutarate Dependent Halogenases.” Chemistry - A European Journal, Jan. 2020, https://doi.org/10.1002/chem.201905752.
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.