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https://doi.org/10.21256/zhaw-19197| Publication type: | Article in scientific journal |
| Type of review: | Peer review (publication) |
| Title: | Complete inclusion of bioactive molecules and particles in polydimethylsiloxane : a straightforward process under mild conditions |
| Authors: | Faccio, Greta Cont, Alice Mailand, Erik Zare-Eelanjegh, Elaheh Innocenti Malini, Riccardo Maniura-Weber, Katharina Rossi, René M. Spano, Fabrizio |
| et. al: | No |
| DOI: | 10.1038/s41598-019-54155-5 10.21256/zhaw-19197 |
| Published in: | Scientific Reports |
| Volume(Issue): | 9 |
| Issue: | 1 |
| Page(s): | 17575 |
| Issue Date: | 2019 |
| Publisher / Ed. Institution: | Nature Publishing Group |
| ISSN: | 2045-2322 |
| Language: | English |
| Subject (DDC): | 572: Biochemistry |
| Abstract: | By applying a slow curing process, we show that biomolecules can be incorporated via a simple process as liquid stable phases inside a polydimethylsiloxane (PDMS) matrix. The process is carried out under mild conditions with regards to temperature, pH and relative humidity, and is thus suitable for application to biological entities. Fluorescence and enzymatic activity measurements show that the biochemical properties of the proteins and enzyme tested are preserved, without loss due to adsorption at the liquid-polymer interface. Protected from external stimuli by the PDMS matrix, these soft liquid composite materials are new tools of interest for robotics, microfluidics, diagnostics and chemical microreactors. |
| URI: | https://digitalcollection.zhaw.ch/handle/11475/19197 |
| Fulltext version: | Published version |
| License (according to publishing contract): | CC BY 4.0: Attribution 4.0 International |
| Departement: | School of Engineering |
| Organisational Unit: | Institute of Computational Physics (ICP) |
| Appears in collections: | Publikationen School of Engineering |
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| File | Description | Size | Format | |
|---|---|---|---|---|
| 2019Faccio_etal_s41598-019-54155-5.pdf | 1.56 MB | Adobe PDF |  View/Open |
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Faccio, G., Cont, A., Mailand, E., Zare-Eelanjegh, E., Innocenti Malini, R., Maniura-Weber, K., Rossi, R. M., & Spano, F. (2019). Complete inclusion of bioactive molecules and particles in polydimethylsiloxane : a straightforward process under mild conditions. Scientific Reports, 9(1), 17575. https://doi.org/10.1038/s41598-019-54155-5
Faccio, G. et al. (2019) ‘Complete inclusion of bioactive molecules and particles in polydimethylsiloxane : a straightforward process under mild conditions’, Scientific Reports, 9(1), p. 17575. Available at: https://doi.org/10.1038/s41598-019-54155-5.
G. Faccio et al., “Complete inclusion of bioactive molecules and particles in polydimethylsiloxane : a straightforward process under mild conditions,” Scientific Reports, vol. 9, no. 1, p. 17575, 2019, doi: 10.1038/s41598-019-54155-5.
FACCIO, Greta, Alice CONT, Erik MAILAND, Elaheh ZARE-EELANJEGH, Riccardo INNOCENTI MALINI, Katharina MANIURA-WEBER, René M. ROSSI und Fabrizio SPANO, 2019. Complete inclusion of bioactive molecules and particles in polydimethylsiloxane : a straightforward process under mild conditions. Scientific Reports. 2019. Bd. 9, Nr. 1, S. 17575. DOI 10.1038/s41598-019-54155-5
Faccio, Greta, Alice Cont, Erik Mailand, Elaheh Zare-Eelanjegh, Riccardo Innocenti Malini, Katharina Maniura-Weber, René M. Rossi, and Fabrizio Spano. 2019. “Complete Inclusion of Bioactive Molecules and Particles in Polydimethylsiloxane : A Straightforward Process under Mild Conditions.” Scientific Reports 9 (1): 17575. https://doi.org/10.1038/s41598-019-54155-5.
Faccio, Greta, et al. “Complete Inclusion of Bioactive Molecules and Particles in Polydimethylsiloxane : A Straightforward Process under Mild Conditions.” Scientific Reports, vol. 9, no. 1, 2019, p. 17575, https://doi.org/10.1038/s41598-019-54155-5.
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