Please use this identifier to cite or link to this item:
https://doi.org/10.21256/zhaw-18883
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DC Field | Value | Language |
---|---|---|
dc.contributor.author | Büchler, Johannes | - |
dc.contributor.author | Papadopoulou, Athena | - |
dc.contributor.author | Buller, Rebecca | - |
dc.date.accessioned | 2019-12-11T10:33:07Z | - |
dc.date.available | 2019-12-11T10:33:07Z | - |
dc.date.issued | 2019-12 | - |
dc.identifier.issn | 2073-4344 | de_CH |
dc.identifier.uri | https://digitalcollection.zhaw.ch/handle/11475/18883 | - |
dc.description.abstract | The introduction of a halogen atom into a small molecule can effectively modulate its properties, yielding bioactive substances of agrochemical and pharmaceutical interest. Consequently, the development of selective halogenation strategies is of high technological value. Besides chemical methodologies, enzymatic halogenations have received increased interest as they allow the selective installation of halogen atoms in molecular scaffolds of varying complexity under mild reaction conditions. Today, a comprehensive library of aromatic halogenases exists, and enzyme as well as reaction engineering approaches are being explored to broaden this enzyme family’s biocatalytic application range. In this review, we highlight recent developments in the sourcing, engineering, and application of flavin-dependent halogenases with a special focus on chemoenzymatic and coupled biosynthetic approaches. | de_CH |
dc.language.iso | en | de_CH |
dc.publisher | MDPI | de_CH |
dc.relation.ispartof | Catalysts | de_CH |
dc.rights | http://creativecommons.org/licenses/by/4.0/ | de_CH |
dc.subject | Flavin-dependent halogenase | de_CH |
dc.subject | Enzyme engineering | de_CH |
dc.subject | Anion promiscuity | de_CH |
dc.subject | Reaction engineering | de_CH |
dc.subject | Co-factor recycling | de_CH |
dc.subject | Biocatalysis | de_CH |
dc.subject.ddc | 660.6: Biotechnologie | de_CH |
dc.title | Recent advances in Flavin-dependent halogenase biocatalysis : sourcing, engineering, and application | de_CH |
dc.type | Beitrag in wissenschaftlicher Zeitschrift | de_CH |
dcterms.type | Text | de_CH |
zhaw.departement | Life Sciences und Facility Management | de_CH |
zhaw.organisationalunit | Institut für Chemie und Biotechnologie (ICBT) | de_CH |
dc.identifier.doi | 10.3390/catal9121030 | de_CH |
dc.identifier.doi | 10.21256/zhaw-18883 | - |
zhaw.funding.eu | No | de_CH |
zhaw.issue | 12 | de_CH |
zhaw.originated.zhaw | Yes | de_CH |
zhaw.pages.start | 1030 | de_CH |
zhaw.publication.status | publishedVersion | de_CH |
zhaw.volume | 9 | de_CH |
zhaw.publication.review | Peer review (Publikation) | de_CH |
zhaw.webfeed | Biokatalyse | de_CH |
zhaw.author.additional | No | de_CH |
Appears in collections: | Publikationen Life Sciences und Facility Management |
Files in This Item:
File | Description | Size | Format | |
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catalysts-09-01030.pdf | 1.95 MB | Adobe PDF | View/Open |
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Büchler, J., Papadopoulou, A., & Buller, R. (2019). Recent advances in Flavin-dependent halogenase biocatalysis : sourcing, engineering, and application. Catalysts, 9(12), 1030. https://doi.org/10.3390/catal9121030
Büchler, J., Papadopoulou, A. and Buller, R. (2019) ‘Recent advances in Flavin-dependent halogenase biocatalysis : sourcing, engineering, and application’, Catalysts, 9(12), p. 1030. Available at: https://doi.org/10.3390/catal9121030.
J. Büchler, A. Papadopoulou, and R. Buller, “Recent advances in Flavin-dependent halogenase biocatalysis : sourcing, engineering, and application,” Catalysts, vol. 9, no. 12, p. 1030, Dec. 2019, doi: 10.3390/catal9121030.
BÜCHLER, Johannes, Athena PAPADOPOULOU und Rebecca BULLER, 2019. Recent advances in Flavin-dependent halogenase biocatalysis : sourcing, engineering, and application. Catalysts. Dezember 2019. Bd. 9, Nr. 12, S. 1030. DOI 10.3390/catal9121030
Büchler, Johannes, Athena Papadopoulou, and Rebecca Buller. 2019. “Recent Advances in Flavin-Dependent Halogenase Biocatalysis : Sourcing, Engineering, and Application.” Catalysts 9 (12): 1030. https://doi.org/10.3390/catal9121030.
Büchler, Johannes, et al. “Recent Advances in Flavin-Dependent Halogenase Biocatalysis : Sourcing, Engineering, and Application.” Catalysts, vol. 9, no. 12, Dec. 2019, p. 1030, https://doi.org/10.3390/catal9121030.
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