Title: Dynamic intraligamentary stabilisation for the treatment of the anterior cruciate ligament rupture : a health technology assessment for Switzerland
Authors : Hess, Sascha
Brunner, Beatrice
Mattli, Renato
Brügger, Urs
Eichler, Klaus
Conference details: 12th HTAi Annual Meeting, Oslo, Norway,13 - 17 June 2015
Issue Date: 2015
License (according to publishing contract) : Licence according to publishing contract
Type of review: Peer review (Abstract)
Language : English
Subject (DDC) : 362: Health and social services
Abstract: Background: In addition to current standard therapies (primary operative ACL reconstruction [pOP], primary conservative treatment with possible delayed ACL repair [pKONS]), a new therapeutic option (dynamic intraligamentary stabilisation [DIS]) has emerged. Objectives: To assess patient benefits and costs of DIS compared to standard therapies (pOP, pKONS) in Switzerland. Methods: A decision tree was developed to analyse cost-effectiveness over two time horizons (2 and 15 years). We performed a literature search for effectiveness and safety outcomes in electronic databases. Effectiveness data were pooled with meta-analysis, where suitable. Direct medical costs and productivity losses were calculated in Swiss Francs (year 2012) using clinical expert information and administrative databases. Results: DIS showed to be at least as effective as the comparators. The ratio of patients at 2 years with equivalent sports level as pre-injury was 49% (95%-CI: 36%-66%) for DIS, 39% (18%-82%) for pOP and 36% (26%-51%) for pKONS. The frequency of safety events was similar for the three strategies. Total costs at 2 years were 21’700 CHF for DIS, 26’000 CHF for pOP and 17’000 CHF for pKONS. Sensitivity analyses did not lead to significantly different conclusions. Conclusions: DIS has the potential to be a valuable treatment option for ACL rupture. However, data is scarce and studies with rigorous design and longer follow-up should be performed.
Departement: School of Management and Law
Organisational Unit: Winterthur Institute of Health Economics (WIG)
Publication type: Conference Poster
URI: https://digitalcollection.zhaw.ch/handle/11475/17001
Appears in Collections:Publikationen School of Management and Law

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